International Journal of Organic Chemistry

Volume 10, Issue 1 (March 2020)

ISSN Print: 2161-4687   ISSN Online: 2161-4695

Google-based Impact Factor: 0.58  Citations  h5-index & Ranking

Synthetic of Some New Fluorine Compounds Bearing 1,2,4-Triazine Moieties and the Related Hetero-Polycyclic Nitrogen Systems as Pharmacological Probes-Overview

HTML  XML Download Download as PDF (Size: 544KB)  PP. 17-38  
DOI: 10.4236/ijoc.2020.101002    137 Downloads   369 Views  

ABSTRACT

This overview summarizes recent advanced literature surveys on the synthesis of fluorine substituted 1,2,4-triazine containing various functional groups and/or the related hetero-polycyclic nitrogen systems have been reported. In addition, physical, chemical, and medicinal properties have been evaluated. The presence of fluorinated atoms often improves these properties with an increasing electronegativity. It, also, enhances the stability of formed carbanion and it improves the hydrophobic effects which have good biological activities.

Cite this paper

Bakhotmah, D. and Alotaibi, F. (2020) Synthetic of Some New Fluorine Compounds Bearing 1,2,4-Triazine Moieties and the Related Hetero-Polycyclic Nitrogen Systems as Pharmacological Probes-Overview. International Journal of Organic Chemistry, 10, 17-38. doi: 10.4236/ijoc.2020.101002.

Cited by

No relevant information.

Copyright © 2020 by authors and Scientific Research Publishing Inc.

Creative Commons License

This work and the related PDF file are licensed under a Creative Commons Attribution 4.0 International License.