Author(s)

Cecilia Zubiri¹, Rosa Ramos², Cecilia Curvale², Raúl Matanó², Roman Bigliardi³, Paula Borobia¹, Anabella Zosi¹, Verónica Garrido⁴, Julieta Hernández⁴, Lucía Gutierrez⁵, Luciana Guzmán¹, María Cristina Arregui¹, Marina Prozzi⁴, Sandro Miculan¹, Viviana Bernedo¹, Maximiliano Fernández Rivas¹, Cristina Lorenzo¹, Florencia Recalde¹, Verónica Valdiviezo¹, Darío Fajre⁶, Cintia Antonioli⁷, Mariana Allende¹, Claudia Losada¹, Teresita Gonzalez¹

¹Department of Gastroenterology at Hospital de Niños Sor María Ludovica, La Plata, Buenos Aires, Argentina.
²Department of Gastroenterology at Hospital de Alta Complejidad El Cruce, Florencio Varela, Buenos Aires, Argentina.
³Posadas Hospital, Buenos Aires, Argentina.
⁴Department of Nutrition at Hospital de Niños Sor María Ludovica, La Plata, Buenos Aires, Argentina.
⁵Department of Surgery at Hospital de Niños Sor María Ludovica, La Plata, Buenos Aires, Argentina.
⁶Department of Otorhinolaryngology at Hospital de Niños Sor María Ludovica, La Plata, Buenos Aires, Argentina.
⁷Department of Pneumonology at Hospital de Niños Sor María Ludovica, La Plata, Buenos Aires, Argentina.

Introduction: Children with surgically repaired esophageal atresia (EA) show esophageal dysmotility. Due to the performance of high-resolution manometry (HRM), three motility alteration patterns have been described, which allowed to know the segmental alterations. Objective: To describe the esophageal motility patterns found through HRM in teenagers with EA and to relate these with the associated esophageal pathology and its severity. Materials and Method: Ten teenagers were included with no history of esophageal blockage or dilations in the last six months, who were orally fed and asymptomatic. Through performance of HRM, we found surgical and endoscopic history, as well as of esophageal biopsies and pH monitoring. Results: We found the following patterns: aperistalsis, pressurization and distal contraction. 70% showed distal contraction, and 100% of esophageal endoscopies and biopsies were normal. 57% of the esophageal pH monitoring analyzed was pathologic. In the pressurization and aperistalsis groups, we observed severe esophagitis and requirement of Nissen antireflux procedure in 100% of the cases. Esophageal pH monitoring analyzed was 100% pathologic. Conclusion: We described the esophageal segmental alterations in teenagers with atresia by means of HRM. The distal contraction group showed better development, without severe esophagitis or requirement of antireflux procedure. Therefore, by performing an HRM in teenagers with EA, we could predict the future esophageal behavior, according to the peristaltic pattern, since there are significant differences among the groups in study.

High-Resolution Manometry, Esophageal Atresia, Teenagers

Zubiri, C. , Ramos, R. , Curvale, C. , Matanó, R. , Bigliardi, R. , Borobia, P. , Zosi, A. , Garrido, V. , Hernández, J. , Gutierrez, L. , Guzmán, L. , Arregui, M. , Prozzi, M. , Miculan, S. , Bernedo, V. , Rivas, M. , Lorenzo, C. , Recalde, F. , Valdiviezo, V. , Fajre, D. , Antonioli, C. , Allende, M. , Losada, C. and Gonzalez, T. (2020) High-Resolution Esophageal Manometry in Teenagers with Esophageal Atresia. Open Journal of Epidemiology, 10, 81-89. doi: 10.4236/ojepi.2020.101007.