Effect of Non-Surgical Periodontal Therapy on the Severity of Rheumatoid Arthritis—A Clinical and Hematological Study ()
Affiliation(s)
1K. M. Shah Dental College and Hospital, Sumandeep Vidyapeeth, Rajkot, India.
2Department of Periodontology, K. M. Shah Dental College and Hospital, Sumandeep Vidyapeeth, Piparia, India.
3K. M. Shah Dental College and Hospital, Sumandeep Vidyapeeth, Surat, India.
ABSTRACT
Background: The epidemiological and pathological relations
between Periodontitis and Rheumatoid arthritis (RA) have been stated. The
citrullination and attendant autoantibody responses are defining features of
RA. It has been recognized that the oral bacteria, inflammation and its
mediators might play an important role in RA activity. Hence this study aimed
to evaluate the effect of Non-surgical Periodontal Therapy in reducing the
severity of Rheumatoid arthritis. Materials and Method: Totally 25
participants diagnosed with RA and Periodontitis were included in the study.
Clinical parameters such as CPSS index, BOP% and CAL, estimation of ESR and
calculation of DAS28 done at baseline, after Pre-NSPT and after next Post-NSPT
were recorded. Results: Statistically
significant improvement was noted for CPSS (p < 0.001), BOP% (p < 0.001)
and CAL (p < 0.001) after NSPT. The ESR values also showed significant
reductions (p < 0.001) and the DAS28 scores also showed statistically
significant improvements (p < 0.001) after NSPT. Conclusion: Reduction in the periodontal inflammation positively affects the rheumatoid
arthritis activity, hence improving the patient’s health.
Share and Cite:
Pandya, R. , Shah, M. and Raval, Y. (2020) Effect of Non-Surgical Periodontal Therapy on the Severity of Rheumatoid Arthritis—A Clinical and Hematological Study.
Open Journal of Stomatology,
10, 1-9. doi:
10.4236/ojst.2020.101001.