International Journal of Organic Chemistry

Volume 9, Issue 1 (March 2019)

ISSN Print: 2161-4687   ISSN Online: 2161-4695

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Synthesis of Some New Thioethers and 4-Thiazolidinones Bearing 3-(Pyridine-4'-yl)-1,2,4-Triazino[5,6-b]Indole Moiety as Antifungal Agents

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DOI: 10.4236/ijoc.2019.91004    541 Downloads   1,002 Views   Citations

ABSTRACT

Some new asymmetric thioethers 5 and 4-thiazolidinones 6 have been obtained from condensation of 5-formyl-3-(pyridin-4'-yl)-1,2,4-triazino[5,6-b] indole (3) with halogenated aromatic amines followed by addition of thiophenol and/or cycloaddition with thiolactic acids in nonpolar solvents. Structures of the products confirmed by elemental analysis and spectral measurements. The new systems obtained were evaluated as antifungal agents.

Cite this paper

Bawazir, W. (2019) Synthesis of Some New Thioethers and 4-Thiazolidinones Bearing 3-(Pyridine-4'-yl)-1,2,4-Triazino[5,6-b]Indole Moiety as Antifungal Agents. International Journal of Organic Chemistry, 9, 37-46. doi: 10.4236/ijoc.2019.91004.

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