Antioxidant Supplement Improves the Pregnancy Rate in Patients Undergoing in Vitro Fertilization for Unexplained Infertility ()
ABSTRACT
Objective: This is a retrospective study to evaluate the
effect of using the antioxidants containing coenzyme Q10 (CoQ10) and omega-3 in
patients undergoing in vitro fertilization and intracytoplasmic sperm injection (IVF-ICSI) for unexplained
infertility. Materials Methods: A total of 299 patients
undergoing IVF-ICSI for unexplained infertility at the IVF center of Ondokuz
Mayis University were studied. The subject group consisted of 135 patients who
used OMEPA Q10 (Co Q10 100 mg, omega-3 600 mg, eicosapentaenoic acid 300 mg,
docosahexaenoic acid 230 mg) for two months before ovarian stimulation. A group
of 164 patients who did not use the supplement were evaluated as the control
group. Results: The pregnancy rate of patients using antioxidants
was statistically higher than that of those who did not use the supplement (p < 0.05). The pregnancy rates of patients in the two
groups were 32.9% and 49.6% respectively. The pregnancy
rate of patients using antioxidants was statistically higher than that of those
who did not use the supplement (p < 0.05) seemed not enough. Conclusion: We concluded that using antioxidants that contain Co
Q10 and omega-3 in patients undergoing IVF-ICSI for unexplained infertility
increased the clinical pregnancy rate. We recommend using antioxidants that contain Co Q10 and omega-3
in infertile patients.
Share and Cite:
Ozdemir, A. , Ayas, B. , Guven, D. , Bakay, A. and Karlı, P. (2019) Antioxidant Supplement Improves the Pregnancy Rate in Patients Undergoing
in Vitro Fertilization for Unexplained Infertility.
Open Journal of Obstetrics and Gynecology,
9, 1-9. doi:
10.4236/ojog.2019.91001.