Pityriasis Alba versus Vitiligo Clinical and Histopathological Study ()
Affiliation(s)
1Department of Dermatology, College of Medicine, University of Baghdad, Baghdad, Iraq.
2Iraqi and Arab Board for Dermatology and Venereology, Baghdad Teaching Hospital, Baghdad, Iraq.
3Department of Dermatology, Baghdad Teaching Hospital, Baghdad, Iraq.
ABSTRACT
Background: Most recently there was a well
established study showed that pityriasis alba of ten
progresses into vitiligo (Sharquie et al.). These
findings were considered a new thought that might support
a new hypothesis regarding the pathogenesis of vitiligo. Objective: In
order to do further work on hypothesis which is in favor that pityriasis alba
might progress into vitiligo, so the present research including clinical and
histopathological study to confirm that pityriasis alba might progress to
vitiligo. Patients and method: This is a descriptive clinical and
histopathological comparative study carried out in Department of Dermatology,
Baghdad Teaching Hospital during the period from January 2015 to August 2016. Thirty
eight patients with pityriasis alba (group A) and twenty eight patients with
vitiligo stage I (group B) and twelve patients with both pityriasis alba and vitiligo (group
C) were included in this study. All patients were fully interviewed and full
history was taken from all the patients. Also careful asking about personal and
family history of vitiligo was taken. Blunt trauma was done to induce Koebner’s phenomenon. Punch
biopsies were taken from skin lesion of all
patients and ten biopsies from 10 persons were taken from normal skin. Each
biopsy specimen was processed and stained with Hematoxylin-eosin (H & E) and
Fontana-Masson (FM) for histological evaluations. Results: Clinical
study-Group A: Pityriasis alba patients: The mean of age of patients in pityriasis alba ± SD
was 8.68 ± 5.94 years including 33 (86.84%) males and 5 (13.16%) females. Koebner’s
phenomenon was positive in 2 (5.26%) patients and family history of vitiligo
was positive in 17 (44.74%) patients. Group B: stage
I vitiligo patients: The mean of age ± SD was 15.46 ± 12.50 years with 15 (57.14%)
male patients and 12 (42.86%) female patients.
A Koebner’s phenomenon was positive in 11 (39.28%) patients
and family history of vitiligo was found in 11 (39.29%)
patients. Group C: pityriasis alba and vitiligo
patients: The mean of age ± SD was 8.33 ± 2.78 years including 9 (75%)
male patients and 3 (25%) female patients. Koebner’s
phenomenon was positive in 6 (50%) patients
and family history of vitiligo was positive in 7 (58.33%) patients. Histopathological study: Group A:
pityriasisalba:
Share and Cite:
Sharquie, K. , Noaimi, A. and Abdulkadhim, L. (2018) Pityriasis Alba versus Vitiligo Clinical and Histopathological Study.
Journal of Cosmetics, Dermatological Sciences and Applications,
8, 140-150. doi:
10.4236/jcdsa.2018.83016.