Author(s)

Juliane Goebel^1*, Felix Nensa¹, Haemi Schemuth¹, Stefan Maderwald², Harald H. Quick^2,3, Thomas Schlosser¹, Kai Nassenstein¹

¹Department of Diagnostic and Interventional Radiology and Neuroradiology, University Hospital Essen, Essen, Germany.
²Erwin L. Hahn Institute for Magnetic Resonance Imaging, University of Duisburg-Essen, Essen, Germany.
³High Field and Hybrid MR Imaging, University of Duisburg-Essen, Essen, Germany.

Background: Recently faster cardiac magnetic resonance (CMR) cine sequences basing on k-t compressed sensing have been developed. Purpose: To compare two compressed sensing CMR sequences-one in breath-hold technique and one during free breathing—with the standard SSFP sequence with respect to regional left ventricular function assessment. Material and Methods: Left ventricular short-axis stacks of two compressed sensing sequences in breath-hold technique (sparse_HB) and during free breathing (sparse_FB; both spatial resolution, 1.8 × 1.8 × 8 mm³) and a standard SSFP cine sequence (spatial resolution, 1.9 × 1.9 × 8 mm³) were acquired in 50 patients on a 1.5 T MR system. Regional wall motion abnormalities (RWMA) were rated qualitatively (normal/hypo-/a-/dyskinesia) by two experienced readers in consensus for all cardiac segments (American Heart Association’s segment model) and sequences. RWMA detection rates were compared between sequences by kappa statistic. Results: In 13 patients, RWMA were detected in at least one cardiac segment. The RWMA detection rates were similar between CMR sequences (hypokinesia, 7.2% to 7.9%; akinesia, 0.8% to 1.3%; dyskinesia 0.3% to 0.4%) and kappa statistics revealed an almost perfect agreement in RWMA detection between both sparse and the standard SSFP sequence (standard versus sparse_HB: kappa, 0.918, p value, <0.001; standard versus sparse_FB: kappa, 0.868, p value, <0.001). Conclusion: Compressed sensing cine CMR acquired during breath-hold or free-breathing allows reliable RWMA detection, thus, might alternatively be used in cine CMR for regional left ventricular function assessment.

Cardiac Imaging Techniques, Cine Magnetic Resonance Imaging, Cardiac Muscle, Cardiac Volume, Myocardial Contraction

Goebel, J. , Nensa, F. , Schemuth, H. , Maderwald, S. , Quick, H. , Schlosser, T. and Nassenstein, K. (2018) Detection of Regional Wall Motion Abnormalities in Compressed Sensing Cardiac Cine Imaging. World Journal of Cardiovascular Diseases, 8, 277-287. doi: 10.4236/wjcd.2018.86027.