Author(s)

Sergio Fasullo^1*, Giorgio Maringhini¹, Piero Fasullo², Filippo Ganci¹, Arcangelo Giamporcaro¹, Sebastiano Scalzo¹, Fernanda Pipitone¹, Vito Pinto¹, Graziella Vetrano¹, Gabriella Terrazzino¹, Stefania Davì³, Nicolò Renda⁴, Antonio Maiorana⁵

¹Division of Cardiology “Paolo Borsellino”, G.F. Ingrassia Hospital, Palermo, Italy.
²Operative Unit of Gynecology, S. Antonio Abate Hospital, Trapani, Italy.
³Chemistry and Pharmaceutical Technologies, University of Palermo, Palermo, Italy.
⁴Psychiatry, CTA La Rinascita, Palermo, Italy.
⁵Operative Unit of Gynecology, ARNAS Civico, Palermo, Italy.

We report a case of arrhythmic storm in a patient with recent vaginal insertion of a device with release of levonorgestrel (synthetic progestin). A woman of 60 years was hospitalized for runs of monomorphic sustained ventricular tachycardia. She received a vaginal device levonorgestrel-releasing 2 days before admission. No history of associated cardiovascular or thyroid disease or risk factors was reported. Laboratory parameters as well as ECG and echocardiogram were normal. After 48 hours from removal of the vaginal device, the patient was asymptomatic and showed only single ectopic beats, sometimes in pairs. The subsequent coronary angiography, electrophysiological study and cardiac magnetic resonance resulted negative.

Levonorgestrel, Progesterone, Ventricular Arrhythmias

Fasullo, S. , Maringhini, G. , Fasullo, P. , Ganci, F. , Giamporcaro, A. , Scalzo, S. , Pipitone, F. , Pinto, V. , Vetrano, G. , Terrazzino, G. , Davì, S. , Renda, N. and Maiorana, A. (2018) Electrical Storms after Levonorgestrel (Synthetic Progestin)-Releasing Intra-Vaginal Device Insertion. A Case Report and a Short Review of Literature. Open Journal of Obstetrics and Gynecology, 8, 338-343. doi: 10.4236/ojog.2018.84037.