Author(s)

Allaoua Kedjadja^1,2*, Abdelmalek Bouraiou³, Rachid Merdes¹

¹Laboratoire de chimie Appliquée, Faculté des Mathématiques et de l’Informatique et des Sciences de la Matière, Université de Guelma, Guelma, Algeria.
²Département de Science de la Matière, Faculté des Science, Université 20 Aout 1955 Skikda, Skikda, Algeria.
³Unité de Recherche de Chimie de l’Environnement et Moléculaire Structurale, Université des Frères Mentouri, Route de Ain El Bey, Constantine, Algeria.

Eight new compounds containing in their structures substituted quinoline and pyrazole entity were synthesized in good to excellent yield by cyclocondensation reaction of chalcones and hydrazine hydrate. This reaction was conducted in formic acid in presence of BF₃·Et₂O or in acetic acid. These approaches were extended to bis-chalcones, which delivered functionalized bispyrazolines. The structures of the prepared compounds were confirmed by IR, ¹HNMR, ¹³CNMR and mass spectral analysis.

Pyrazoline, Chalcone, Quinoline, Cyclocondensation

Kedjadja, A. , Bouraiou, A. and Merdes, R. (2018) Synthesis and Spectral Characterization of Novel 2-Pyrazoline and Bis-2-Pyrazoline Containing Quinoline Moiety. International Journal of Organic Chemistry, 8, 105-114. doi: 10.4236/ijoc.2018.81006.