Journal of Biosciences and Medicines

Volume 5, Issue 2 (February 2017)

ISSN Print: 2327-5081   ISSN Online: 2327-509X

Google-based Impact Factor: 0.51  Citations  

Antioxidant and Antifungal Activity of Naphthoquinones Dimeric Derived from Lawsone

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DOI: 10.4236/jbm.2017.52004    1,583 Downloads   3,592 Views  Citations

ABSTRACT

This article reports the evaluation of antioxidant and antifungal activity from synthetic naphthoquinones derived from lawsone. The antifungal activity was carried out through the inhibition of exoenzymes produced by Candida albicans. The inhibition of phospholipase and the proteinase production by Candida was similar in all derivatives tested; however, the difference between the enzyme production of the control and test does not show statistical difference in any of the studied strains. Furthermore, the antioxidant activity using DPPH radical-scavenging assay showed an important activity for all naphtoquinone derivatives.

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Oliveira, A. , Brighente, I. , Lund, R. , Llanes, L. , Nunes, R. , Bretanha, L. , Yunes, R. , Carvalho, P. and Ribeiro, J. (2017) Antioxidant and Antifungal Activity of Naphthoquinones Dimeric Derived from Lawsone. Journal of Biosciences and Medicines, 5, 39-48. doi: 10.4236/jbm.2017.52004.

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