Author(s)

Irtiza Hasan^1,2*, Tasnuva Rashid³, Md. Harun Ur Rashid Bhuiyan⁴

¹Cardiology, Canterbury Christ Church University, Kent, UK.
²Internal Medicine, The University of Edinburgh, Edinburgh, UK.
³Department of Epidemiology, School of Public Health, The University of Texas HSC, Houston, TX, USA.
⁴Clinical & Interventional Cardiology, Z. H. Sikder Cardiac Care & Research Centre, Dhaka, Bangladesh.

Use of Statin is a cornerstone in modern day medical practice and an essential component for primary prevention of cardiovascular diseases (CVD). Various evidences exemplify and resonate the importance of Statins in reducing CVD mortality and improvement of survivability. However, there is a continental variation in recent guidelines directing lipid-lowering therapy in regards to aim, dose, timing as well as the protocol for initiation of therapy. Similar uncertainties exist with regards to the generalizability of the finding from available evidence, a variation of benefits of Statin with respect to age and gender, the validity of the research conducted and actual gain in survivability and mortality benefits. Thus, there is a need for looking at the actual indications, risk-benefit ratios and cost effectiveness before tediously prescribing Statin for the primary prevention of CVDs. This paper will attempt to critically review the evidence behind the uses of Statins in the primary prevention of CVDs.

Statin, Cholesterol, Cardiovascular Diseases, Primary Prevention

Hasan, I. , Rashid, T. and Rashid Bhuiyan, M. (2016) A Critical Evaluation of the Role of Routine Uses of Statin as a Tool for Primary Prevention of Cardiovascular Diseases. Open Journal of Preventive Medicine, 6, 133-142. doi: 10.4236/ojpm.2016.64012.