Open Access Library Journal

Volume 1, Issue 2 (May 2014)

ISSN Print: 2333-9705   ISSN Online: 2333-9721

Google-based Impact Factor: 0.47  Citations  

Arylidene Derivatives as Synthons in Heterocyclic Synthesis

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DOI: 10.4236/oalib.1100367    3,360 Downloads   5,932 Views  Citations
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ABSTRACT

This review describes the synthetic procedures for the preparation of arylideneacetophenones, arylidenecycloalkanones, 2-arylidene-1-indanones, 2-arylidene-1-tetralones, 2-arylidene-1-benzosuberones, aurones, 1-thioaurones, 3-arylidene-4-chromanones, 3-arylidene-1-thio-4-chromanones, 3-arylideneflavanones, 3-arylidene-1-thioflavanones, arylideneanilines, arylidenemalononitriles, diethylarylidenemalonates, ethylarylidenecyanoacetates, arylidenecyanoacetamides, 5-arylidene derivatives of barbituric and thiobarbituric acids, arylidene derivatives of Meldrum’s acid and arylidene derivatives of dimedone. Also, it demonstrates the reactivity of these arylidene derivatives in heterocyclic synthesis with emphasis on the most recent findings. Some of these are the α,β-enones, víz. aurones and 3-arylidene-4-chromanones belong to the natural products. The others are synthetic substances which are convenient and important intermediates for the synthesis of a variety of useful and novel heterocyclic systems.

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El-Gohary, N. (2014) Arylidene Derivatives as Synthons in Heterocyclic Synthesis. Open Access Library Journal, 1, 1-47. doi: 10.4236/oalib.1100367.

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