Open Journal of Rheumatology and Autoimmune Diseases

Volume 5, Issue 4 (November 2015)

ISSN Print: 2163-9914   ISSN Online: 2164-005X

Google-based Impact Factor: 0.32  Citations  

Biologic Agents in Behçet’s Disease: Our Experience and Review of the Literature

HTML  XML Download Download as PDF (Size: 352KB)  PP. 97-103  
DOI: 10.4236/ojra.2015.54016    3,424 Downloads   4,252 Views  


Behcet’s disease (BD) is a large vessel vasculitis with a wide range of clinical manifestations. Some of these manifestation may be life threatening and rapid suppression of the inflammation with effective immunosuppressive agent is crucial. There are traditional drugs with different response rates and all have efficacy on different manifestations of the disease. The most frightening manifestations of the disease are ocular, neurologic, intestinal and vascular types of involvement. Besides benign and easily treated manifestations there are also refractory cases with complicated involvement. The novel biologic agents have been used for these resistant patients and favorable response rates have been reported. In this review, we have shared our experience with biologic agents in BD and also reviewed the literature for the efficacy and safety for these novel agents for refractory patients.

Share and Cite:

Yeşil, N. , Şahin, H. , Işık, H. , Örnek, Z. , Yazgan, S. , Tok, A. , Yandı, Y. , Işık, M. and Doğan, İ. (2015) Biologic Agents in Behçet’s Disease: Our Experience and Review of the Literature. Open Journal of Rheumatology and Autoimmune Diseases, 5, 97-103. doi: 10.4236/ojra.2015.54016.

Cited by

No relevant information.

Copyright © 2023 by authors and Scientific Research Publishing Inc.

Creative Commons License

This work and the related PDF file are licensed under a Creative Commons Attribution 4.0 International License.