Journal of Biosciences and Medicines

Volume 3, Issue 10 (October 2015)

ISSN Print: 2327-5081   ISSN Online: 2327-509X

Google-based Impact Factor: 0.51  Citations  

“Pyridopyridazine”: A Versatile Nucleus in Pharmaceutical Field

HTML  XML Download Download as PDF (Size: 348KB)  PP. 59-66  
DOI: 10.4236/jbm.2015.310008    3,164 Downloads   4,624 Views  Citations

ABSTRACT

Pyridopyridazines are an important kind of nitrogen atom containing heterocyclic compounds due to their synthetic and pharmacological versatility. This fused heterocycle system represents a common structural feature for many bioactive compounds showing a variety of pharmacological activities which makes it an attractive scaffold for the design and development of new drugs. This mini review summarizes an updated information described in recent literature, about the most relevant pharmacological properties of pyridopyridazines derivatives.

Share and Cite:

Ibrahim, M. , Elmenoufy, A. , Elagawany, M. , Ghoneim, M. and Moawad, A. (2015) “Pyridopyridazine”: A Versatile Nucleus in Pharmaceutical Field. Journal of Biosciences and Medicines, 3, 59-66. doi: 10.4236/jbm.2015.310008.

Cited by

[1] Synthetic Pathways to Pyrido[3,4-c]pyridazines and Their Polycyclic Derivatives
Organics, 2022
[2] Structure and cytotoxic properties of 1-hydroxy-5-methyl-7-phenylpyrido [3, 4-d] pyridazin-4 (3H)-one and its mono-and disubstituted ethyl acetates
… Section C: Structural …, 2022
[3] Reactive Oxygen Species-Mediated Apoptosis and Cytotoxicity of Newly Synthesized Pyridazin-3-Ones In P815 (Murin Mastocytoma) Cell Line
2019
[4] In Vitro Antitumor Activity of Newly Synthesized Pyridazin-3 (2H)-One Derivatives via Apoptosis Induction
Pharmaceutical Chemistry Journal, 2018
[5] Cytotoxicity of new pyridazin‐3(2H)‐one derivatives orchestrating oxidative stress in human triple‐negative breast cancer (MDA‐MB‐468)
Archiv der Pharmazie, 2018
[6] Molecular Modelling, Synthesis and Evaluation of Pyridazine Derivatives as Potent Anti-Cancer Agents
2016
[7] Biological Potential and Chemical Properties of Pyridine and Piperidine Fused Pyridazine Compounds: Pyridopyridazine a Versatile Nucleus
2016

Copyright © 2024 by authors and Scientific Research Publishing Inc.

Creative Commons License

This work and the related PDF file are licensed under a Creative Commons Attribution 4.0 International License.