Author(s)

Ying Zhu^1*, Augustine Tuck Lee Tan²

¹Mathematics and Mathematics Education, National Institute of Education, Nanyang Technological University, Singapore.
²Natural Sciences and Science Education, National Institute of Education, Nanyang Technological University, Singapore.

Ganoderma lucidum(G. lucidum) spores as a valuable Chinese herbal medicine have vast marketable prospect for its bioactivities and medicinal efficacy. This study aims at the development of an effective and simple analytical method to distinguish G. lucidum spores from its fruiting body, which is of essential importance for the quality control and fast discrimination of raw materials of Chinese herbal medicine. Attenuated total reflection Fourier transform infrared (ATR-FTIR) spectroscopy combined with the appropriate chemometric methods including penalized discriminant analysis, principal component discriminant analysis and partial least squares discriminant analysis has been proven to be a rapid and powerful tool for discrimination of G. lucidum spores and its fruiting body with classification accuracy of 99%. The model leads to a well-performed selection of informative spectral absorption bands which improve the classification accuracy, reduce the model complexity and enhance the quantitative interpretations of the chemical constituents of G. lucidum spores regarding its anticancer effects.

Feature Selection, Attenuated Total Reflection Fourier Transform Infrared Spectroscopy, Penalized Linear Discriminant Analysis, Principal Component Discriminant Analysis, Partial Least Squares Discriminant Analysis

Zhu, Y. and Tan, A. (2015) Chemometric Feature Selection and Classification of Ganoderma lucidum Spores and Fruiting Body Using ATR-FTIR Spectroscopy. American Journal of Analytical Chemistry, 6, 830-840. doi: 10.4236/ajac.2015.610079.