This paper studies the influence of entrepreneurship education on students’ entrepreneurial abilities from the perspective of social network. In four college students’ entrepreneurship case studies from one university, we adopted methodological triangulation and multiple methods to guarantee the reliability and validity of the research. We proposed that courses and projects in entrepreneurship education formed social network among mentors, monitors, and students, in which knowledge could flow frequently. We then discussed the influence of projects pattern, mentor pattern, and monitors pattern on college students’ entrepreneurial abilities respectively, by analyzing the structure and ties of the social network. This research contributed to social network theory and entrepreneurship education both theoretically and practically.