Author(s)

J. Munné¹, F. Alameda^1,2*, A. Bergueiro³, G. Mancebo^2,3, L. Garrigós⁴, T. Baró¹, B. Lloveras¹, J. Gimeno¹, R. Carreras^2,3, S. Serrano^1,2

¹Department of Pathology, Hospital del Mar, Barcelona, Spain.
²Universitat Autonoma de Barcelona, Barcelona, Spain.
³Department of Obstetrics and Gynecology, Hospital del Mar, Barcelona, Spain.
⁴Department of Oncology, Hospital del Mar, Barcelona, Spain.

Endometrial carcinoma is the most frequent genital tract malignancy. The first symptom (guide-symptom) is usually metrorrhagia; however, in around 10% of cases it is not. In contrast, osseous metastases are infrequent in endometrial cancer. The bones of the pelvis and lower extremities are those most frequently involved in disseminated metastatic diseases. In these cases, endometrial cancer is usually high grade (Grade III). Case report: 56-year-old woman who presented right inguinal pain. The X-ray showed a lithic lesion in the right ischium. A histopathological study demonstrated a metastatic lesion, suspected to be endometrial cancer. The computer tomography scan revealed a uterine mass and a second lithic lesion in the right tibia. The patient received chemotherapy (carboplatin and paclitaxel), and the bone lesions were irradiated. The patient is still alive 18 months after the diagnosis. This case emphasizes the importance of considering an endometrial primary tumor when evaluating bone metastasis of unknown primary cancer.

Osseous Metastasis, Endometrial Carcinoma, Immunohistochemistry

Munné, J. , Alameda, F. , Bergueiro, A. , Mancebo, G. , Garrigós, L. , Baró, T. , Lloveras, B. , Gimeno, J. , Carreras, R. and Serrano, S. (2015) Unusual Presentation of Endometrial Cancer: A Clinicopathological Study of One Case. Open Journal of Obstetrics and Gynecology, 5, 23-27. doi: 10.4236/ojog.2015.51004.