Author(s)

Aaron J. Smith, John Oertle, Dino Prato

Envita, Scottsdale, AZ, USA.

Chronic Lyme disease is predicated by an infection with Borrelia burgdorferi via tick vector. B. burgdorferi has been extensively researched with regard to its genome and cell biology. There are many unique characteristics to the bacteria itself; however, serological diagnostics and diagnosis based on symptoms can be complicated and potentially misleading. Other promising diagnostics were also evaluated in this review. Treatment of the chronic Lyme disease can be complicated and at times ineffective. The purpose of this review is to examine B. burgdorferi from a biological and clinical perspective.

Lyme Disease, Borrelia Burgdorferi, Genome, Cellular Process, Epidemiology, CD57, C4a, Diagnostics, Treatment

Smith, A. , Oertle, J. and Prato, D. (2014) Borrelia burgdorferi: Cell Biology and Clinical Manifestations in Latent Chronic Lyme. Open Journal of Medical Microbiology, 4, 210-223. doi: 10.4236/ojmm.2014.44023.