In this study, different fuel combinations that can be adopted to reduce the level of air pollution and GHG emissions associated with the energy generation are assessed; and the air pollution and global warming effects of the Jamaican electricity generation fuel mix are determined. Based on the energy production and consumption patterns, and global warming potentials; the authors conclude that: Increase in energy consumption and generation yields increase in emissions of major air pollutants and GHGs; Choice of the fuel mix determines the success of GHG emissions reductions; and there is no single fuel that is not associated with GHG or other air pollution or environmental degradation implications.