At present, a sound intellectual property management and service system have not been established yet in Chinese colleges and universities. Meanwhile, the lost of existing intellectual property in universities due to small amount, low conversion rate, low technology content and weak brand awareness, hinders the positive effect of intellectual property and affects its transformation and application in China. This article introduces the current problems with intellectual property in universities and gives some countermeasures to promote the use of intellectual property in universities for a better regional economic service.