International Journal of Clinical Medicine
Volume 5, Issue 3 (January 2014)
ISSN Print: 2158-284X ISSN Online: 2158-2882
Google-based Impact Factor: 0.52 Citations h5-index & Ranking
Vitamin E Therapy in Non-Alcoholic Fatty Liver Disease ()
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ABSTRACT
Non-alcoholic fatty liver disease (NAFLD) is closely related to oxidative stress. Vitamin E (VE) is an effective antioxidant, which could relieve NAFLD symptoms by improving the balance of oxidation and anti-oxidation. However, recent researches indicate that the functional mechanisms of VE are not only limited to anti-oxidation, but also include adjusting the metabolism disorders of glucose and lipid. Furthermore, the efficacy of VE remains controversial in the treatment of NAFLD by far, and the suitable condition of patient, drug dosage, drug safety and course of treatment during clinical application still need to be discussed. Therefore, this paper reviewed the recent study progresses of clinical application of VE alone and VE and other drugs.
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