Pharmacology & Pharmacy
Volume 4, Issue 9 (December 2013)
ISSN Print: 2157-9423 ISSN Online: 2157-9431
Google-based Impact Factor: 0.70 Citations h5-index & Ranking
In Vitro Preliminary Evidences on the Antioxidant Properties of Biogenic Amines ()
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ABSTRACT
Antioxidant properties of the principal biogenic amines were determined in vitro by four analytical methods—Folin Ciocalteu, DPPH, enzymatic and inhibition of lipid peroxidation—in order to avoid possible measuring-method linked mistakes. Different results are obtained, depending on the parameters that each of them measures. The combination of the data indicates that all examined amines show antioxidant characteristics: in particular, tyramine, serotonin, L-norepinephrine, (-)-epinephrine and dopamine owing to their (poly)phenolic structure too, while aliphatic polyamines-spermine, spermidine, putrescine and cadaverine-histamine, melatonin and tryptamine appear to act specifically on the oxygen-consuming species involved in the lipid peroxidation of polyunsaturated fatty acids.
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