Author(s)

N. Behtash, M. Karimi Zarchi, A. A. Shamshirsaz, A. A. Shamshirsaz, Ashrafosadt Miratashi-Yazd, N. Mehrdad

Gynecological Oncology Fellowship, Shahid Sadoughi University of Medical Science, Yazd, Iran.

Background: Primary choriocarcinoma of the cervix is a very rare entity. Case: A 35-year-old patient had been admitted to our hospital with vaginal bleeding for 7 months. A cervical mass measured 4 × 4 cm was palpated on the anterior surface of the cervix. Biopsy of the lesion demonstrated extensive necrosis and was in favor of squamous cell carcinoma. Patient was accepted as FIGO stage I_b1-2 and underwent type II hysterectomy with bilateral salpingoopherectomy and bilateral pelvic lymph node dissection was carried out. Post operative pathologic evaluation of the surgical specimen evinced that the case was primary cervical choriocarcinoma. Conclusion: Primary choriocarcinoma of the cervix should be considered in patients in their reproductive years with cervical lesion and negative cervical cytology. Beta-hCG assay and transvaginal color Doppler sonography are useful for early diagnosis.

Choriocarcinoma; Cervix; Primary

N. Behtash, M. Zarchi, A. Shamshirsaz, A. Shamshirsaz, A. Miratashi-Yazd and N. Mehrdad, "Primary Cervical Choriocarcinoma: Case Report and the Review of Literatures," Journal of Cancer Therapy, Vol. 4 No. 8, 2013, pp. 1335-1340. doi: 10.4236/jct.2013.48158.