Wrist diseases, also known as “mama hand”, “mouse hand” or “keyboard hand”, are commonly seen and easily over-looked symptoms in daily life. The diseases are mostly related to incorrect exercise or excessive force imposed on hands, leading to tenosynovitis or carpal tunnel syndrome. To alleviate the symptoms or even to recover, besides drug treatment, supplementary rehabilitation training is necessary. The rehabilitation process forces the affected wrist area to continually exercise in order to stimulate the self-repair signals sent to the affected area for partial restoration, if not all, of the supposed functions. In modern world, using information technology to improve the rehabilitation environment with better approaches has become a trend. In this study, software programs coded in C# and Flash are developed to work on the Bluetooth ball hardware to facilitate the rehabilitation. The basic principle is to use the reaction from the Bluetooth ball’s swaying or swinging to drive the movement of the objects on the computer screen, making the supposedly boring rehabilitation much more fun and vivid in the interactive multimedia environment, thus gaining better treatment effect. Also, RFID, Internet and databases can be integrated into this facility to provide patient identification and data storage for references in making rehabilitation training programs.