Author(s)

Emmanuel Chanda, Alister Kandyata, Javan Chanda, Kumar S. Baboo

Department of Biological Sciences, School of Natural Sciences, University of Zambia, Lusaka, Zambia.
Department of Community Medicine, School of Medicine, University of Zambia, Lusaka, Zambia.
Directorate of Public Health and Research, National Malaria Control Centre, Ministry of Health, Lusaka, Zambia.

Expansive chemical-based vector control has resulted in development of vector resistance to different insecticides harnessed for prevention of disease transmission in public health. The environmentally safe insect growth regulators and microbial larvicides provide potential tools for insecticide resistance management. The efficacy and persistence of Dimilin GR-2% and Mosquiron 10 EC insect growth regulators were evaluated against Anopheles gambiae s.l larvae under laboratory and simulated field conditions. In laboratory bio-efficacy trials, complete emergence inhibition was achieved at higher concentrations with 96 hours post exposure of mosquito aquatic stages to the two larvicides. In simulation field trials, persistence of both larvicides at higher concentrations increased gradually with complete inhibition attained at 7 days and maintained up to 21 days. In the quest of deploying non insecticide based interventions for a sustainable environment, insect growth regulators can be recommended for operational scale larviciding for mosquito larval control in the context of integrated vector management.

Evaluation; Insect Growth Regulators; Integrated Vector Management; Malaria Control

Chanda, E. , Kandyata, A. , Chanda, J. and Baboo, K. (2013) Bio-efficacy and persistence evaluation of Dimilin^®GR-2% and Mosquiron^® 10 EC insect growth regulators against Anopheles gambiae s.l (diptera: Culicidae) larvae. Journal of Biomedical Science and Engineering, 6, 11-16. doi: 10.4236/jbise.2013.67A1003.