Open Journal of Pathology

Volume 3, Issue 3 (July 2013)

ISSN Print: 2164-6775   ISSN Online: 2164-6783

Google-based Impact Factor: 0.31  Citations  

Pleomorphic Adenoma with Exuberant Squamous Metaplasia and Keratin Cysts Mimicking Squamous Cell Carcinoma in Minor Salivary Gland

HTML  XML Download Download as PDF (Size: 578KB)  PP. 113-116  
DOI: 10.4236/ojpathology.2013.33020    6,012 Downloads   10,020 Views  Citations

ABSTRACT

Salivary gland tumors, the second most common neoplasm of the mouth after squamous cell carcinoma, account for a significant proportion of tumors of the oral and perioral regions. An unusual case of adenoma presented as a solitary intraoral palatine mass in a 32-year-old woman is reported here. The tumor was interpreted as an unusual pleomorphic adenoma because of the presence of exuberant squamous metaplasia, clinically mimicking squamous cell carcinoma. Moreover, the presence of cystic structures filled with keratinized material was also salient feature. Pleomorphic adenomas may occasionally display focal squamous metaplastic changes; when extensive, it presents the potential for misinterpretation of the histology as indicative of well-differentiated squamous cell carcinoma.

Share and Cite:

S. Lim, I. Cho, J. Park and S. Lim, "Pleomorphic Adenoma with Exuberant Squamous Metaplasia and Keratin Cysts Mimicking Squamous Cell Carcinoma in Minor Salivary Gland," Open Journal of Pathology, Vol. 3 No. 3, 2013, pp. 113-116. doi: 10.4236/ojpathology.2013.33020.

Cited by

[1] Expression of p16Ink4a protein in pleomorphic adenoma and carcinoma ex pleomorphic adenoma proves diversity of tumour biology and predicts clinical course
Journal of Clinical …, 2022
[2] Keratinizing pleomorphic adenoma: A rare variant in an unusual location
Journal of Oral and …, 2021
[3] Expression of p16Ink4a protein in pleomorphic adenoma and carcinoma ex pleomorphic adenoma proves diversity of tumour biology and predicts clinical …
2021
[4] Salivary gland pleomorphic adenomas presenting with extremely varied clinical courses. A single institution case-control study
2021
[5] Pleomorphic Adenoma with Extensive Squamous and Adipocytic Metaplasia Mimicking as Low Grade Mucoepidermoid Carcinoma on FNAC
2020
[6] Pleomorphic adenoma of soft palate with extensive squamous metaplasia–A diagnostic enigma
2019
[7] Keratinizing Pleomorphic Adenoma in Minor Salivary Gland: A Case Report.
2019
[8] CYTOLOGICAL VARIATIONS AND DIAGNOSTIC CHALLENGES IN PLEOMORPHIC ADENOMAS
2018
[9] Keratinizing pleomorphic adenoma: An unusual case report
Journal of oral and maxillofacial pathology: JOMFP, 2018
[10] Squamous Metaplasia in Pleomorphic Adenoma: A Diagnostic and Prognostic Enigma
2018
[11] CYSTIC SQUAMOUS METAPLASIA OF PLEOMORPHIC ADENOMAIN PALATE: A RARE CASE REPORT
INTERNATIONAL JOURNAL OF ADVANCES IN CASE REPORTS, 2017
[12] Florid keratin pearls in pleomorphic adenoma-A mimicker to malignancy
2017
[13] Florid Squamous Metaplasia and Keratin Cyst Formation in Palatal Minor Salivary Gland Tumor: A Diagnostic Challenge.
International Journal of Health Sciences and Research (IJHSR), 2016
[14] Cystic Change in Pleomorphic Adenoma: A Rare Finding and a Diagnostic Dilemma.
Journal of Clinical & Diagnostic Research, 2015

Copyright © 2024 by authors and Scientific Research Publishing Inc.

Creative Commons License

This work and the related PDF file are licensed under a Creative Commons Attribution 4.0 International License.