A Biphenotypic (Mixed Phenotypic) Acute Leukemia: Report of Two Cases with Immunophenotypic Study - Open Journal of Blood Diseases

OJBD > Vol.3 No.2, June 2013

Open Journal of Blood Diseases

Volume 3, Issue 2 (June 2013)

ISSN Print: 2164-3180 ISSN Online: 2164-3199

Google-based Impact Factor: 0.56 Citations

A Biphenotypic (Mixed Phenotypic) Acute Leukemia: Report of Two Cases with Immunophenotypic Study ()

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DOI: 10.4236/ojbd.2013.32014 5,188 Downloads 9,480 Views Citations

Author(s)

Anupam Sarma, Jagannath Dev Sharma, Chidananda Bhuyan, Munlima Hazarika, Amal Chandra Kataki

Affiliation(s)

Department of Gynecologic Oncology, Dr. B. Borooah Cancer Institute, Guwahati, India.
Department of Medical Oncology, Dr. B. Borooah Cancer Institute, Guwahati, India.
Department of Pathology, Dr. B. Borooah Cancer Institute, Guwahati, India.

ABSTRACT

Biphenotypic acute leukemia (BAL) is an uncommon clinical entity. It is a type of acute leukemia with features characteristic of both the myeloid and lymphoid lineages and for this reason is designated as mixed-lineage, hybrid or biphenotypic acute leukemia. As strict diagnostic criteria have only recently been established, the precise incidence among acute leukemia is uncertain, although it is likely to account for approximately less then 5% of all acute leukemia. BAL is now collectively considered as “mixed phenotype acute leukemia” (MPAL). We hereby report two cases of a rare disease, BAL from our institution in the light of morphology, cytochemistry, flow cytometry and review of literature regarding these cases are described.

KEYWORDS

Biphenotypic Acute Leukaemia (BAL); Mixed Phenotype Acute Leukemia (MPAL); Flow Cytometry;Cytochemistry

Share and Cite:

Sarma, A. , Sharma, J. , Bhuyan, C. , Hazarika, M. and Kataki, A. (2013) A Biphenotypic (Mixed Phenotypic) Acute Leukemia: Report of Two Cases with Immunophenotypic Study. Open Journal of Blood Diseases, 3, 65-68. doi: 10.4236/ojbd.2013.32014.

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