Hierarchy of Protein Loop-Lock Structures: A New Server for the Decomposition of a Protein Structure into a Set of Closed Loops - Computational Molecular Bioscience

CMB > Vol.3 No.1, March 2013

Volume 3, Issue 1 (March 2013)

ISSN Print: 2165-3445 ISSN Online: 2165-3453

Google-based Impact Factor: 1.76 Citations

Hierarchy of Protein Loop-Lock Structures: A New Server for the Decomposition of a Protein Structure into a Set of Closed Loops ()

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DOI: 10.4236/cmb.2013.31001 3,358 Downloads 7,686 Views Citations

Author(s)

Simon Kogan, Zakharia Frenkel, Oleg Kupervasser, Zeev Volkovich

Affiliation(s)

Department of Software Engineering, ORT Braude College, Karmiel, Israel.
Genome Diversity Center, Institute of Evolution, University of Haifa, Haifa, Israel.
Transist Video Limited Liability Company, Skolkovo, Russia.

ABSTRACT

HoPLLS (Hierarchy of protein loop-lock structures) (http://leah.haifa.ac.il/~skogan/Apache/mydata1/main.html) is a web server that identifies closed loops-a structural basis for protein domain hierarchy. The server is based on the loop-and-lock theory for structural organisation of natural proteins. We describe this web server, the algorithms for the decomposition of a 3D protein into loops and the results of scientific investigations into a structural “alphabet” of loops and locks.

KEYWORDS

Structural Alphabet; Loop-Lock Structure; Web Server; Protein; Amino Acids

Share and Cite:

S. Kogan, Z. Frenkel, O. Kupervasser and Z. Volkovich, "Hierarchy of Protein Loop-Lock Structures: A New Server for the Decomposition of a Protein Structure into a Set of Closed Loops," Computational Molecular Bioscience, Vol. 3 No. 1, 2013, pp. 1-8. doi: 10.4236/cmb.2013.31001.

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