Author(s)

Gaspard Tékpa^1,2, Hermione Dahlia Mossoro-Kpinde^3,4*, Jessy Guylaine Nazilari¹, Gertrude Komoyo¹, Saint Calvaire Henri Diémer⁴

¹Centre Hospitalier Universitaire de l’Amitié, Bangui, Central African Républic (CAR).
²Département de Médecine, Faculté des Sciences de la Santé, Université de Bangui, Bangui, Central African Republic (CAR).
³Direction de la Médecine du Travail, Ministère du Travail, de l’emploi et de la Protection Sociale, Bangui, Central African Républic (CAR).
⁴Département de Santé Publique, Faculté des Sciences de la Santé, Université de Bangui, Bangui, Central African Républic (CAR).

Objective: HIV-HBV co-infection is a major public health problem that has not been sufficiently explored in the Central African workplace. The aim of this study was to assess the frequency of HIV-HBV co-infection among people who living with HIV (PLHIV) in the infectious and tropical diseases department of the Centre Hospitalier Universitaire de l’Amitié Sino-Centrafricaine in Bangui. Methods: A retrospective study was carried out from January 1, 2010 to December 31, 2021 in the Infectious and Tropical Diseases Department at the Amitié Sino-Centrafricaine University Hospital. It included the files of all PLHIV, which included the results of HBV serology. A standardized form was used to collect socio-demographic and professional data by documentary review. Data was analysed using Epi-Info 7 software. Means, proportions were calculated as well as Chi square witch was significant if p-value was below 0.05. Results: The study included 265 patients, 188 were women (70.1%) and 77 men (29.1%), giving a sex ratio of 0.45. Mean age was 35.8 years, higher in men (40 years) than in women (35.8 years) (p ˂ 0.0001). The age groups 25 to 34 (37.7%) and 35 to 44 (33.6%) were in the majority (71.3%). The majority of PLHIV were unemployed (57.1%), including housewives (43.0%). HBV prevalence was 14.3%, including 7.2% among the unemployed, who account for half of all co-infections. The search for associations between HIV-HBV co-infection and all socio-demographic characteristics (age, sex, marital status) and socio-professional categories showed no significant difference (p ≥ 0.05). Conclusion: PLHIV were predominantly young adults, female, and unemployed; no occupation was significantly associated with co-infection. The vast majority of co-infected people were not covered by the occupational health system (unemployed or informal sector). Urgent action is needed to improve workers’ access to occupational medicine in CAR.

People Living with HIV, HIV-HBV Co-Infection, Occupation, Informal Sector

Tékpa, G. , Mossoro-Kpinde, H. , Nazilari, J. , Komoyo, G. and Diémer, S. (2024) Socio-Demographic and Occupational Aspects of HIV-HBV Co-Infection in Bangui, Central African Republic (CAR): Hospital-Based Cross-Sectional Study. Advances in Infectious Diseases, 14, 310-321. doi: 10.4236/aid.2024.142023.