Results of Surgical Management of Malignant Obstruction of the Common Bile Duct in Yaoundé ()
Author(s)
Eric Patrick Savom1,2,
Gaël Tsanga Nomo2,
Richard II Mbele2,
Mahamat Yannick Ekani Boukar3,
Cédric Paterson Atangana2,
Fred Dikongue Dikongue4,
Guy Aristide Bang2,5,
Arthur Essomba2,5
Affiliation(s)
1Yaoundé General Hospital, Yaoundé, Cameroon.
2Faculty of Medicine and Biomedical Sciences of the Universityof Yaoundé I, Yaoundé, Cameroon.
3Faculty of Health Sciences, University of Buea, Buea, Cameroon.
4Faculty of Medicine and Biomedical Sciences of the University of Dschang, Dschang, Cameroon.
5Yaoundé Teaching Hospital, Yaoundé, Cameroon.
ABSTRACT
Introduction: In Cameroon, surgery remains the only approach in malignant obstructions of the common bile duct (MOCBD) even in palliative situations. The aim of this work was to describe the modalities of surgical treatment of MOCBD, evaluate the results and detect the factors associated with postoperative morbidity and mortality. Patients and Methods: We conducted an analytical observational study, with retrospective data collection from the files of patients operated upon for MOCBD. This was done in four referral hospitals in the city of Yaoundé for a 42-month period spanning from January 1, 2020 to June 30, 2023. Demographic data, clinical presentation, surgical data, and 30-day postoperative outcomes were collected. Results: We collected 71 files. The sex ratio was 1.4 and the mean age was 56 ± 11 years. Fifty-three (53) patients (74.6%) were overweight or obese and 10 patients (14.1%) were hypertensive. A clinical cholestasis syndrome was present in 69 patients (97.2%). Fifty-five (55) patients (77.5%) had a cancer of the head of the pancreas, 8 patients (11.3%) had an extra-hepatic cholangiocarcinoma and 8 patients (11.3%) had an ampullary adenocarcinoma. Eight (8) resections (11.3%) with curative intent had been carried out and in 63 cases (88.7%), surgery was palliative. Postoperative morbidity was 55.7%, influenced by advanced WHO stage (p = 0.02). Postoperative mortality was 25.7%, associated with a high ASA score (p = 0.01). Conclusion: Pancreatic head cancer is the main etiology of malignant obstructions of the common bile duct in Cameroon. Surgical treatment is most often palliative. Postoperative morbidity and mortality are high, influenced by high WHO and ASA scores.
Share and Cite:
Savom, E.P., Tsanga Nomo, G., Mbele, R.II, Ekani Boukar, M.Y., Atangana, C.P., Dikongue Dikongue, F., Bang, G.A. and Essomba, A. (2024) Results of Surgical Management of Malignant Obstruction of the Common Bile Duct in Yaounde.
Surgical Science,
15, 265-277. doi:
10.4236/ss.2024.154025.
Cited by
No relevant information.