Author(s)

Abdullah Al-Mamari¹, Saleem Almiyah²

¹Department of Biological Sciences, Faculty of Science, Ibb University, Ibb, Yemen.
²Faculty of Dentistry, Lower Shabelle University, Mogadishu, Somalia.

Background: Several conducted studies have reported a higher and more frequent Helicobacter pylori infection rate in type 2 diabetes mellitus (T2DM). The aim of this study was to estimation the prevalence of H. pylori and its association between H. pylori infection and T2DM. Materials and Methods: A sectional-cross study was conducted based on 200 patients studded with socioeconomic characteristics through a questionnaire & H. pylori was diagnosed by serum anti-H. pylori immunoglobulin G (IgG) and IgA. Furthermore, patients were investigated for fasting blood glucose (FBG) levels, glycosylated hemoglobin (HbA1c), serum cholesterol, and other biochemistry parameters. Results: The findings showed The prevalence of Hp positive infection was significantly higher in the total sample was 134 with (67%). While 66 out of 200 patients with (33%) was H. pylori negative infection. of H. pylori. Further, the mean values were statistically significant for diabetes with H. pylori infection for IgG > 300 titer and IgA > 250 titer, regarding, HbA1C (7.52 ± 0.41) (P < 0.001), FBG, LHDL, triglyceride levels, uric acid and BMI (kg/m²). The diabetic patients showed a higher prevalence rate of symptoms with ulcer stomach 47 (45.63%), muscular symptoms 36 (34.95%) and nausea 7 (22.58%). Conclusions: The current study revealed that H. pylori prevalence infections were significantly higher in diabetic patients studied compared to non-diabetic patients. Furthermore, T2DM patients infected with H. pylori positive reported a higher prevalence rate of symptoms than H. pylori negative.

Diabetes, Helicobacter pylori Infection, Prevalence, Immunoglobulin G, Gastritis

Al-Mamari, A. and Almiyah, S. (2024) Estimate the Prevalence of Helicobacter pylori Infection among Diabetes & Non-Diabetes Mellitus Patients and Its Correlation with Malignant Gastritis Patients Attending in Lower Shabelle Region (Somalia). Journal of Biosciences and Medicines, 12, 38-48. doi: 10.4236/jbm.2024.124004.