Author(s)

Amadou Yaya Diallo^1,2, Mamadou Mouctar Diallo^1,2, Mamadou Dian Barry^2,3, Kadiatou Mamadou Bobo Barry^1,2, Saikou Oumar Diallo^1,2, Djenabou Diallo^1,2, Soriba Bangoura^1,2, Mamadou Malal Diallo^1,2, Thierno Mamadou Oury Diallo^2,3, Mohamed Lamine Kaba^1,2, Alpha Oumar Bah^1,2

¹Department of Nephrology-Hemodialysis, CHU Donka, Conakry, Guinea.
²Faculty of Health Sciences and Techniques, Gamal Abdel Nasser University of the Republic of Guinea, Conakry, Guinea.
³Department of Urology-Andrology, CHU Ignace Deen, Conakry, Guinea.

Introduction: Acute obstructive renal failure (AORF) is a frequent clinical situation, secondary to obstruction of the urinary excretory tract. Whatever the cause, urinary tract obstruction suddenly opposes glomerular filtration and is responsible for tubulointerstitial lesions. It accounts for 10% of acute renal failure (ARF). The aim of this study was to identify the causes and prognosis of cases of acute obstructive renal failure managed at the Centre National d’hémodialyse Donka. Material and Methods: This was a prospective descriptive study lasting 6 months, from September 1, 2022 to February 29, 2023. All patients undergoing haemodialysis for acute obstructive renal failure who agreed to participate in the study and whose medical records were complete were included. Results: During the course of the study, we registered 97 haemodialysis patients, including 20 cases (20.62%) of acute obstructive renal failure. The mean age of the patients was 57.8 ± 10.54 years, with a male predominance of 11 cases (55%) and a sex ratio of 1.22. The reasons for consultation were dominated by physical asthenia 11 cases (55%), lumbar pain 9 cases (50%), vomiting 6 cases (30%) and acute urine retention 6 cases (30%). Arterial hypertension 16 cases (80%) and urinary tract infection 10 cases (50%) were the most common antecedents. The etiologies of RAOI were dominated by lithiasis 10 cases (50%), neoplasia 6 cases (30%) and benign prostatic hypertrophy 3 cases (15%). mean creatinine was 1267.60 ± 710.76 μmol/l with extremes of 243 μmol/l and 2822 μmol/l, mean urea was 39.56 ± 18.36, hyperkalemia in 14 cases (70%) and hyponatremia in 8 cases (40%). After hemodialysis, 9 cases (45%) recovered renal function, 4 cases (20%) became chronic and 7 cases (35%) died. Conclusion: The frequency of AKI remains non-negligible in our department, and early detection and prompt management would considerably reduce the morbidity and mortality associated with this pathology.

Acute Obstructive Renal Failure, Hemodialysis, Prognosis, Donka

Diallo, A. , Diallo, M. , Barry, M. , Barry, K. , Diallo, S. , Diallo, D. , Bangoura, S. , Diallo, M. , Diallo, T. , Kaba, M. and Bah, A. (2024) Causes and Prognosis of Cases of Acute Obstructive Renal Failure Managed at the Donka National Hemodialysis Center. Open Journal of Nephrology, 14, 136-146. doi: 10.4236/ojneph.2024.142014.