Author(s)

Monzango Sibo^1,2, Mboloko Esimo¹, Mputu Lobota¹, Mbemba Fundu³, Nganga Mireille⁴, Itewa Monka^1,2, Mayoka Mamoi^1,2, Ntanga Kabuya^1,2, Amba Naomie², Lezaka Ensemeya², Bola Jonita², Maxime Fastrez⁵, Lebwaze Bienvenu⁶, Balthazar Phoba⁷, Destin Mbongi⁷, Tshilolo Léon⁷, Kahindo P. Muyalalo¹, Mbanzulu Pita¹, Emile Darai⁸

¹Department of Gynecology and Obstetrics, Faculty of Medicine, University Clinics of Kinshasa, Kinshasa, Democratic Republic of the Congo.
²Department of Gynecology, Service of Laparoscopic Surgery, Onyx Medical Center, Kinshasa, Democratic Republic of the Congo.
³Department of Biology, Faculty of Science, University of Kinshasa, Kinshasa, Democratic Republic of the Congo.
⁴Department of Medical Biology, Faculty of Medicine, University Clinics of Kinshasa, Kinshasa, Democratic Republic of the Congo.
⁵Department of Gynecology and Obstetrics, Erasme Endometriosis Clinic, Free University of Brussels, Brussels, Kingdom of Bel-gium.
⁶Department of Histopathology, Faculty of Medicine, University Clinics of Kinshasa, Kinshasa, Democratic Republic of the Congo.
⁷Institute of Biomedical Research (IRB), Health Training and Support Center (CEFA) Monkole, Kinshasa, Democratic Republic of the Congo.
⁸Department of Gynecology and Obstetrics, Tenon Hospital, Sorbonne University, Paris, France.

Context: Vitamin E is a powerful antioxidant and plays an important role in human reproduction. However, micronutrient deficiency is a major public health problem, particularly in developing countries. This study aimed to establish reference intervals (RIs) for vitamin E in black Congolese people of childbearing age using an ELISA method to provide a reference for clinically assessing vitamin E status. Methods: A total of 127 healthy people between the ages of 20 and 42 who underwent check-ups were randomly selected for the study. ELISA method measured the level of vitamin E. The effect of gender on vitamin E level was assessed, and RI was established using a parametric approach. Results: Women showed significantly higher levels of vitamin E than men (p = 0.01). The RI of vitamin E in people of childbearing age was 3.71 to 13.72, 4.52 to 14.64, and 4.17 to 13.52 mg/L, respectively, for the whole population, women and men. Conclusion: Using an ELISA method, this study established RI for vitamin E in the black Congolese population of childbearing age. We also found that women had significantly higher vitamin E levels than men. The results could provide a scientific basis for interpreting vitamin status in people of childbearing age in our setting.

ELISA, Reference Interval, People of Childbearing Age, Vitamin E

Sibo, M. , Esimo, M. , Lobota, M. , Fundu, M. , Mireille, N. , Monka, I. , Mamoi, M. , Kabuya, N. , Naomie, A. , Ensemeya, L. , Jonita, B. , Fastrez, M. , Bienvenu, L. , Phoba, B. , Mbongi, D. , Léon, T. , Muyalalo, K. , Pita, M. and Darai, E. (2023) Serum Vitamin E Reference Intervals in a Black Congolese Population of Kinshasa. Open Journal of Obstetrics and Gynecology, 13, 737-744. doi: 10.4236/ojog.2023.134062.