Author(s)

Sangaré Drissa^1,2, Cissé Sékou Mamadou^1,2, Guindo Youssouf^2,3, Abdoulaye Diawara^2,4, Diakité Niagalé^2,5, Boly Berthé Bréhima^2,6, Keita Kaly^2,7, Issa Diallo¹, Traore Djenebou^7,8, Soucko Kaya Assetou^7,8

¹Internal Medicine Unit, Kayes Hospital, Kayes, Mali.
²National Center for Scientific and Technological Research (CNRST), Bamako, Mali.
³Cardiology Unit, Kayes Hospital, Kayes, Mali.
⁴Imaging Unit, Kayes Hospital, Kayes, Mali.
⁵Nephrology Unit, Kayes Hospital, Kayes, Mali.
⁶Army Health Service, Bamako, Mali.
⁷Point G Hospital Internal Medicine Department, Bamako, Mali.
⁸Faculty of Medicine of Bamako, Bamako, Mali.

Introduction: Urinary tract infection is one of the most frequent public health problems in the world and concerns all ages. Objective: To describe the epidemiological, clinical and biological profile of urinary tract infection in the internal medicine unit of the Fousseyni Daou hospital in Kayes. Methodology: It was a descriptive and cross-sectional study with retrospective data collection which took place from January 1 to December 31, 2020 at the Internal Medicine Unit of the Fousseyni Daou Hospital in Kayes. It covered all outpatients and hospitalized patients presenting with a urinary tract infection during the study period. Results: We identified 79 cases of urinary tract infection out of 145 requests for ECBU, that is a positivity rate of 53.10% and out of a total of 1883 admissions that is a hospital prevalence of 4.19%. The age groups of 36 to 45 years and 46 to 55 years were more represented in 28 cases (35.44%) and 25 cases (31.64%) with an average age of 45 years ± 10. The female sex was predominant, 42 cases (53.16%) with a sex ratio of 0.88. Housewives were more represented 28 cases (34.44%). The majority of patients resided in rural areas 49 cases (62.03%). The history was dominated by the following pathologies: hypertension 48.10%, diabetes 36.70% and gastropathy 30.37%. The main clinical manifestations were: Urinary burning 67 cases (84.81%), Dysuria 65 cases (82.27%), Pelvic pain 59 cases (74.68%), Fever 57 cases (72.15%). The epidemiological profile of the isolated strains was dominated by enterobacteriaceae, followed by gram-positive cocci and gram-negative bacilli. The main bacteria responsible for urinary tract infections in order of frequency: Escherichia coli (45.56%), Klebsiella pneumoniae (11.39%), Pseudomonas aeruginosa (8.86%), Staphylococcus aureus (7.59%), Streptococcus sp (6.33%), Enterobacter cloacae (3.79%), Acinetobacter sp (3.79%). The study of the susceptibility and resistance profiles of the isolated strains showed significant sensitivity of enterobacteriaceae to colistin and resistance to amoxicillin and to the amoxicillin + clavulanic acid combination. Conclusion: Urinary tract infections are a major public health problem since they are responsible for significant morbidity and mortality and a high cost of care. Knowledge of the epidemiological-clinical and bacteriological profile of these infections is essential for efficient management.

Urinary Tract Infection, Epidemiology, Clinic, Bacteriology, Internal Medicine, Fousseyni Daou Hospital, Kayes, Mali

Drissa, S., Mamadou, C.S., Youssouf, G., Diawara, A., Niagalé, D., Bréhima, B.B., Kaly, K., Diallo, I., Djenebou, T. and Assetou, S.K. (2023) Epidemiological, Clinical, Bacteriological Profile of Urinary Tract Infection in the Internal Medicine Unit of the Fousseyni Daou Hospital in Kayes. Open Journal of Internal Medicine, 13, 62-75. doi: 10.4236/ojim.2023.131007.