Author(s)

Loubna Saadaoui¹, Fatima Zahra Lahmamssi¹, Hayat Aynaou^1,2,3, Houda Salhi^1,2,3, Nadia Alaoui Ismaili^2,3,4, Hanan El Ouahabi^1,2,3

¹Department of Endocrinology, Diabetology and Nutrition, Hassan II University Hospital, Fez, Morocco.
²Faculty of Medicine and Pharmacy of Fez, Sidi Mohamed Ben Abdullah University, Fez, Morocco.
³Laboratory of Epidemiology and Research in Health Sciences, Fez, Morocco.
⁴Nuclear Medicine Department, Hassan II University Hospital, Fez, Morocco.

Introduction: The impact of pregnancy on the prognosis of papillary thyroid carcinoma (PTC) has been debated for several decades; however, no definitive conclusions have been reached. The main objective of this study is to demonstrate the short-term influence of pregnancy on the evolution and prognosis of PTC. Materials and Methods: A prospective descriptive and analytical study was conducted in the Endocrinology and Diabetology Department at the Hassan II University Hospital in Fez, including patients followed for papillary thyroid carcinoma presenting with a pregnancy during the year 2019 and 2020. The follow-up of these patients was continued until 1 year postpartum. We studied the clinical, paraclinical and therapeutic factors that could influence the prognosis of the disease. Results: We included 26 patients. Our study showed a significant correlation between recurrence and the presence of unfavorable histological signs (p = 0.02) as well as the initial Tg level (0.01). However, pregnancy was not an influencing factor (p = 0.41). Conclusion: Pregnancy does not seem to be a factor aggravating the prognosis of differentiated thyroid cancers.

Papillary Thyroid Carcinoma, Well Differentiated, Pregnancy, Recurrence, Prognostic Factors

Saadaoui, L. , Lahmamssi, F. , Aynaou, H. , Salhi, H. , Ismaili, N. and El Ouahabi, H. (2023) Papillary Thyroid Carcinoma and Pregnancy: What Impact on Prognosis?. Case Reports in Clinical Medicine, 12, 22-29. doi: 10.4236/crcm.2023.121004.