Author(s)

Jinze Pei, Ning Wei, Congcong Cui, Guangshan Xuan^*

College of Chemical Engineering, Qingdao University of Science & Technology, Qingdao, China.

In recent years, natural biodegradable nanoparticles as stabilizers of Pickering emulsions have attracted extensive attention. In this work, a Pickering emulsion composed of chitosan/Arabic gum nanoparticles (CS/GA NPs), tea tree oil and vitamin E was formulated. Then the antibacterial, anti-inflammatory and wound healing abilities of the emulsion were evaluated. Pickering emulsion encapsulated the tea tree oil strengthened antibacterial activity towards Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa and Candida albicans. Besides, this multi-phase system offered a platform to load with vitamin E, which provides anti-inflammatory effects while antibacterial. Meanwhile, Pickering emulsion avoided contact between bacteria and skin when used in wound treatment.

Pickering Emulsion, CS/GA Nanoparticles, Tea Tree Oil, Vitamin E, Antibacterial, Anti-Inflammatory, Wound Healing

Pei, J. , Wei, N. , Cui, C. and Xuan, G. (2022) Preparation of Pickering Emulsion for Antibacterial, Anti-Inflammatory and Wound Healing. Journal of Biosciences and Medicines, 10, 134-150. doi: 10.4236/jbm.2022.1012012.