Author(s)

Modou Ndongo^1*, Nestor Nankeu², Josephine Nkok², Helene Messet², Fabrice Tiako², Mamadou Mouctar Diallo², Misylias Bouaoud², Attia Houyem², Fatiha Lahouel², Djillali Ziane Berroudja², Tayeb Bensalem², Sid Ali Toufik Benyaghla², Catherine Albert², Sidy Mohamed Seck³, El Hadji Fary Ka¹

¹Department of Nephrology, Dialysis and Kidney Transplantation of Aristide Le Dantec Hospital, Dakar, Senegal.
²Department of Nephrology, Dialysis of Louis Pasteur Hospital, Chartres, France.
³Department of Nephrology, Dialysis of Ouakam Military Hospital, Dakar, Senegal.

Calcific uremic arteriolopathy (CUA) is a rare pathology affecting 5% of dialysis patients but with a poor prognosis. It is characterized by calcification and thrombotic lesions of the microcirculation leading to hyperalgesic ischemic skin lesions. Several risk factors have been identified, mainly warfarin treatment, mineral and bone disorders (MBD), inflammation and malnutrition. In the evocative forms, the diagnosis is made based upon the physical examination finding of classic painful ulcerated lesions that are covered by a black eschar. Skin biopsy, due to the risk of aggravation and delayed healing, is only performed in case of doubt diagnosis. The therapeutic attitude due to the lack of solid randomized studies is based on expert consensus and requires a multidisciplinary approach. We report here the case of a patient with CUA revealed in the form of multiple ulcerative-necrotic skin lesions associated with pressure sores and arterial wounds.

Calcific Uremic Arteriolopathy, Calciphylaxis, Hemodialysis

Ndongo, M. , Nankeu, N. , Nkok, J. , Messet, H. , Tiako, F. , Diallo, M. , Bouaoud, M. , Houyem, A. , Lahouel, F. , Berroudja, D. , Bensalem, T. , Benyaghla, S. , Albert, C. , Seck, S. and Ka, E. (2022) Calcific Uremic Arteriolopathy or Calciphylaxis in a Hemodialysis Patient: Case Study and Review of the Literature. Open Journal of Nephrology, 12, 303-310. doi: 10.4236/ojneph.2022.123031.