Author(s)

Eloísa Helena Kubiszeski^1,2*, Maria Aparecida Mazzutti Verlangieri Do Carmo^2,3, Anselmo Verlangieri Do Carmo^2,3, Marcial Francis Galera^1,4

¹Federal University of Mato Grosso, Postgraduate Program in Health Sciences, Faculty of Medicine, Cuiabá, Brazil.
²Women’s Health Care Unit, Júlio Müller University Hospital, UFMT, EBSERH, Cuiabá, Brazil.
³Federal University of Mato Grosso, Department of Gynecology and Obstetrics, Faculty of Medicine, Cuiabá, Brazil.
⁴Federal University of Mato Grosso, Department of Pediatrics, Faculty of Medicine, Cuiabá, Brazil.

Objective: This study aims to describe the demographic and evolutionary characteristics of pregnant and postpartum women with the novel coronavirus disease (COVID-19) who were admitted to a medium-sized hospital in Brazil. Methods: This descriptive and retrospective study collected data from medical records at a hospital in Cuiabá (MT) from March 2020 to October 2021. Results: Pregnant and postpartum women with COVID-19 who needed hospitalization were predominantly mixed-race, from metropolitan areas, and carriers of moderate and severe forms of the disease. The most prevalent comorbidities in this group were pre-gestational diabetes, hypertension, asthma, and autoimmune disease, with the primary risk factors being overweight and obesity. Furthermore, elevated lactate dehydrogenase (LDH), C-reactive protein (CRP), and D-dimer levels were the relevant laboratory findings in this group of patients. The most frequent maternal outcomes were respiratory failure, invasive ventilatory support, thromboembolic phenomena, sepsis, and preterm labor. Maternal death occurred in 6.4% of pregnant women. Preterm birth and the need for neonatal intensive care units (NICU) were significant complications in neonates; stillbirth/neonatal mortality rate is 11.0%. Conclusion: This study’s findings revealed that the clinical conditions at hospitalization were associated with worse living conditions and lack of access to healthcare, resulting in an increased likelihood of severity and deteriorating outcomes in this group of women and neonates.

Analysis of Consequences, Coagulation Disorders, Coronavirus Disease 2019, Intensive Care, Maternal Mortality, Neonatal Outcomes, Pregnancy, SARS-CoV-2

Kubiszeski, E. , Carmo, M. , Carmo, A. and Galera, M. (2022) Clinical and Evolutionary Characteristics of Pregnant and Postpartum Women with COVID-19 Admitted to a Hospital in the Central Region of Brazil. Open Journal of Obstetrics and Gynecology, 12, 770-783. doi: 10.4236/ojog.2022.128066.