Effects of Common Myokines on Diabetes Mellitus ()
Author(s)
Yu Zhu1,2*,
Qingqing Liu1*,
Yurong Zhu1*,
Tiantian Guo1,
Mengtong Jin1,
Jiali Hao1,
Chao Qi1,
Xiaofeng Miao1,
Duan Xi1,
Jiamao Fan1#,
Jin Li2
ABSTRACT
Diabetes mellitus, a type of chronic metabolic disease, is occurring more frequently and causes
severe threats to human health. In vivo,
exercise can stimulate skeletal muscle cells to secrete and release myokines into
blood circulation, which will participate in metabolism and act on multiple organs
or systems. Recently, the relationship between myokines and diabetes mellitus was
a hot research topic, and myokines may be potential targets for the diagnosis,
monitoring, prevention and treatment of diabetes mellitus. In this review, we elucidated the multiple effects of common
myokines in the pathogenesis and therapy of diabetes mellitus, which
will provide a theoretical foundation of the mechanism in the positive effects
of exercises on humans.
Share and Cite:
Zhu, Y. , Liu, Q. , Zhu, Y. , Guo, T. , Jin, M. , Hao, J. , Qi, C. , Miao, X. , Xi, D. , Fan, J. and Li, J. (2022) Effects of Common Myokines on Diabetes Mellitus.
Journal of Diabetes Mellitus,
12, 153-166. doi:
10.4236/jdm.2022.123013.
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