Author(s)

Daniele Melo Sardinha^1*, Diana da Costa Lobato², Ana Lúcia da Silva Ferreira³, Karla Valéria Batista Lima³, Ricardo José de Paula Souza e Guimarães¹, Luana Nepomuceno Gondim Costa Lima^1,3

¹Post-graduate Program in Epidemiology and Health Surveillance of the Instituto Evandro Chagas (PPGEVS/IEC), Ananindeua, Pará, Brazil.
²State Coordinator of the Reference Center for Special Immunobiologicals from the Pará State Public Health Department (CRIE/SESPA), Belém, Pará, Brazil.
³Post-Graduation Program in Parasite Biology in the Amazon, University of state of Pará, Instituto Evandro Chagas (PPGBPA/UEPA/IEC), Belém, Pará, Brazil.

Objective: To analyze the severe cases of COVID-19 in Brazil in 2020 and compare those vaccinated and unvaccinated against influenza in invasive ventilation, admission in Intensive Care Unit (ICU) and deaths. Method: Cross-sectional study with public data from the OpenDataSUS platform, regarding confirmed severe cases for COVID-19 in Brazil in the year 2020. Data were analyzed by SPSS, from the chi-square test of independence and binary logistic regression. Results: The population was 472,688 cases and 177,640 deaths, with a lethality of 37.58% in severe cases. The test of independence was highly significant in vaccinated survivors (<0.0001), and regression showed an almost twofold odds ratio for invasive ventilation, ICU admission, and death in unvaccinated cases. Conclusion: We recommend mass influenza vaccination as an adjuvant in combating the COVID-19 pandemic in Brazil.

COVID-19, Pandemic, Brazil, Influenza Vaccine

Sardinha, D. , Lobato, D. , Ferreira, A. , Lima, K. , de Paula Souza e Guimarães, R. and Gondim Costa Lima, L. (2021) Analysis of 472,688 Severe Cases of COVID-19 in Brazil Showed Lower Mortality in Those Vaccinated against Influenza. World Journal of Vaccines, 11, 28-32. doi: 10.4236/wjv.2021.113004.