Author(s)

Dohoué Patricia Eliane Agbanglanon^1*, Imane M’barki¹, Oswald Houessou¹, Gaël Kietga¹, Siham Jaba¹, Hafsa Elouazzani², Séka Evrard Narcisse¹, Hanan Elkacemi¹, Nadia Cherradi², Sanaa Elmajjaoui¹, Noureddine Benjaafar¹

¹Department of Radiotherapy Oncology, National Institute of Oncology, Rabat, Morocco.
²Department of Pathological Anatomy Laboratory, Specialties Hospital, Rabat, Morocco.

Introduction: Rhabdomyosarcoma (RMS) is the most common soft tissue tumor in children, with the head and neck location accounting for up to 40% of cases. The embryonal and alveolar histologic variants are more commonly seen in pediatric patients. The treatment is multimodal and the prognosis of this clinical entity is always gloomy. We report the case of nasopharyngeal rhabdomyosarcoma in a 7-year-old boy child with a good response to early post-therapy. Case Presentation: The patient was diagnosed with nasopharyngeal RMS revealed by a congested nose, ptosis and bilateral blindness, and who received induction chemotherapy followed by concurrent radiotherapy followed by adjuvant chemotherapy. The evolution is marked by a good clinical course but persistence of bilateral blindness. Conclusion: The RMS nasopharyngeal often presents with nonspecific symptoms. Multimodal therapy should be performed including surgery, chemotherapy and radiotherapy.

Rhabdomyosarcoma, Nasopharyngeal, Pediatric, Chemotherapy, Radiotherapy

Agbanglanon, D. , M’barki, I. , Houessou, O. , Kietga, G. , Jaba, S. , Elouazzani, H. , Narcisse, S. , Elkacemi, H. , Cherradi, N. , Elmajjaoui, S. and Benjaafar, N. (2021) Pediatric Nasopharyngeal Rhabdomyosarcoma: About a Case and Review of Literature. Journal of Cancer Therapy, 12, 10-18. doi: 10.4236/jct.2021.121002.