Mechanical Ventilation Outcomes at the NICU at EL-Zahraa University Hospital ()
Affiliation(s)
1Bachelor of Medicine and Surgery, Mansoura University, Mansoura, Egypt.
2Pediatrics and Neonataology Department, Faculty of Medicine for Girls, Al-Azhar University, Cairo, Egypt.
3Pediatric and Neonataology Department, Al Zahraa University Hospital, Faculty of Medicine for Girls, Al-Azhar University, Cairo, Egypt.
ABSTRACT
Background: Mechanical ventilation
(MV) is one of the most common therapies in the neonatal Intensive Care Unit
(NICU) and is associated with increased morbidity and mortality. MV is a
complex and highly specialized area in neonatology that has several
complications related to different modes, techniques, and devices. Aim of the Study: To detect the causes of morbidity and mortality in mechanically
ventilated neonates and to correlate the neonatal morbidity and mortality with
gestational age, birth weight and duration of MV. Patients
and Methods: This prospective observation analytical study was carried out on 110
neonates who were admitted to NICU at Al-Zahraa university hospital on MV
during the period from March 2019 to March 2020. All neonates were followed up
till the time of discharge with record of any complications during mechanical
ventilation. Detailed medical history, examination to detect indication of MV
and laboratory, radiological
investigations were recorded. As
regard the general characterization of studied neonates, 64 (58.2%) were males
while the rest 46 (41.8%) were females, 50 (45.4%) were full term (37 - 42 wks), 42 (38.18%) were early preterm (28 - 33 wks), 18
(16.3%) were late preterm (34 - 42 wks). Results: Among (110 mechanically ventilated
neonates, 58.2%
were males, 41.8% were females. The most common indication for MV in the
studied cases was respiratory distress syndrome (RDS) in 30% neonates.
Ventilator associated pnemonia and Devices associated infection were the most
common complications related to MV (19.1% and 11.8% respectively). While septic
shock and multiorgan failure were the most common complications related to the
underlying disease (24%). There is a significant negative association between
gestational age, birth weight and mortality in mechanically ventilated
neonates. the
overall recovery was 59.1% among studied neonates. Conclusion: Respiratory
disorders were the commonest indication of MV in NICU mostly RDS. Ventilator
associated pneumonia and devices associated infection are common complications.
Preterm and low birth weight neonates are vulnerable group for need of
mechanical ventilation.
Share and Cite:
Othman, A. , Oshaib, Z. and Moneim, M. (2020) Mechanical Ventilation Outcomes at the NICU at EL-Zahraa University Hospital.
Open Journal of Pediatrics,
10, 732-743. doi:
10.4236/ojped.2020.104074.
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