Journal of Materials Science and Chemical Engineering

Volume 8, Issue 10 (October 2020)

ISSN Print: 2327-6045   ISSN Online: 2327-6053

Google-based Impact Factor: 0.72  Citations  

Establishment of PEEK-Associated Drug Delivery Systems—Limits and Perspectives

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DOI: 10.4236/msce.2020.810004    328 Downloads   1,024 Views  Citations

ABSTRACT

In order to enhance promising properties of polyethertherketone (PEEK) for biomedical application, we evaluate two different strategies for the provision of PEEK with a drug delivery system at the example of the model drug chlorhexidine diacetate. On one hand we discuss the deposition of a biodegradable polymeric drug-release coating, based on well-established poly(L-lactide) (PLLA), on PEEK and on the other hand the modification of PEEK via sulfonation and its subsequent drug loading. Results are compared to pure PLLA-associated drug delivery systems and limits and perspectives are shown.

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Behnecke, M. and Petersen, S. (2020) Establishment of PEEK-Associated Drug Delivery Systems—Limits and Perspectives. Journal of Materials Science and Chemical Engineering, 8, 32-41. doi: 10.4236/msce.2020.810004.

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