Open Access Library Journal

Volume 7, Issue 10 (October 2020)

ISSN Print: 2333-9705   ISSN Online: 2333-9721

Google-based Impact Factor: 0.73  Citations  

Polynomial-Based Smoothing Estimation for a Semiparametric Accelerated Failure Time Partial Linear Model

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DOI: 10.4236/oalib.1106824    242 Downloads   665 Views  Citations
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ABSTRACT

The accelerated failure time partial linear model allows the functional form of the effect of covariates to be possibly nonlinear and unknown. We propose to approximate the nonparametric component by cubic B-splines and construct a Gehan estimating function similar to that under the AFT model. Due to its non-smoothness, which will lead to computational challenge in estimating standard error, we propose a polynomial-based smoothing Gehan estimating function and compute the estimate of the parameters involved using the limited memory Broyden-Fletcher-Goldfarb-Shanno algorithm. Asymptotic properties of the resulting estimators are established. The proposed method presents a good performance in the simulation studies and is applied to two real data sets.

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Chen, W. and Ren, F.L. (2020) Polynomial-Based Smoothing Estimation for a Semiparametric Accelerated Failure Time Partial Linear Model. Open Access Library Journal, 7, 1-15. doi: 10.4236/oalib.1106824.

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