Efficacy of Perioperative Intravenous Lidocaine for Multimodal Analgesia ()
ABSTRACT
Given the rising incidence of opioid misuse and opioid-related deaths worldwide, it is imperative to find nonopioid analgesic adjuncts for perioperative pain management. Perioperative opioid exposure in opioid-naïve patients for even minor surgical procedures may result in significant opioid dependence. Although the use of intravenous lidocaine in the perioperative period is not novel, recently it has been proposed as an important adjunct to multimodal analgesia. In addition to improving acute pain, lidocaine may reduce the incidence of chronic post-operative pain syndrome (CPPS), improve bowel function, and decrease post-operative nausea and vomiting (PONV) thereby speeding up the post-operative recovery process. Furthermore, lidocaine has efficacy in a variety of procedures including abdominal, gynecological, and urological surgeries. The aim of this narrative review is to evaluate the effects of intravenous lidocaine compared to traditional analgesic methods on post-operative pain control and recovery for various surgical procedures.
Share and Cite:
Lockwood, N. and Misra, L. (2020) Efficacy of Perioperative Intravenous Lidocaine for Multimodal Analgesia.
Open Journal of Anesthesiology,
10, 299-312. doi:
10.4236/ojanes.2020.109027.