Author(s)

Rafael Giovani Missé¹, Luiz Felipe Adsuara de Sousa¹, Lucas de Macedo dos Santos², Abrahão Fontes Baptista^2,3, Clarice Tanaka², Julia Maria D’Andréa Greve⁴, Samuel Katsuyuki Shinjo^1*

¹Division of Rheumatology, Faculdade de Medicina FMUSP, Universidade de Sao Paulo, Sao Paulo, SP, Brazil (BR).
²Department of Physical Therapy, Speech Therapy and Occupational Therapy, Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, Sao Paulo, SP, Brazil (BR).
³Center for Mathematics, Computing and Cognition, Universidade Federal de ABC, SP, Brazil (BR).
⁴Laboratory of Movement Studies, Institute of Orthopedics and Traumatology, Hospital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, Brazil (BR).

Transcranial direct current stimulation (tDCS) has emerged as a nonpharmacological tool in physical rehabilitation. There have currently no studies that evaluated the safety and efficacy of tDCS in patients with dermatomyositis. Case-report: Three adult women with dermatomyositis were allocated randomly to intervention (i-tDCS, one patient) or not (sham-tDCS, two patients) of three consecutive days of tDCS and evaluated in four periods: before-tDCS (PRE), 15 minutes after-tDCS (0th POST), 15 days after-tDCS (15th POST), and 30 days after-tDCS (30th POST). The tDCS was safe throughout the protocol, without disease relapsing or adverse effects related to tDCS. Furthermore, the tDCS increased the muscle torque and total work of dominant and non-dominant elbow flexors in the patient with i-tDCS, when compared to two patients with sham-tDCS. Conclusions: The tDCS was safe and appeared to influence long-term strength in the limb of the patient with stable dermatomyo-sitis.

Dermatomyositis, Neuromodulation, Safety, Systemic Autoimmune Myopathies

Missé, R. , Sousa, L. , Santos, L. , Baptista, A. , Tanaka, C. , Greve, J. and Shinjo, S. (2020) Safety of Transcranial Direct Current Electrical Stimulation in Dermatomyositis: A Case Report. Open Journal of Rheumatology and Autoimmune Diseases, 10, 88-93. doi: 10.4236/ojra.2020.102011.