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Molecular and Behavioral Neuroprotective Effects of Clavulanic Acid and Crocin in Haloperidol-Induced Tardive Dyskinesia in Rats
Molecular Neurobiology,
2025
DOI:10.1007/s12035-024-04566-x
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[2]
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Therapeutic Potential of Saffron Extract in Mild Depression: A Study of Its Role on Anhedonia in Rats and Humans
Phytotherapy Research,
2025
DOI:10.1002/ptr.8424
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[3]
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Effect of Saffron Versus Selective Serotonin Reuptake Inhibitors (SSRIs) in Treatment of Depression and Anxiety: A Meta-analysis of Randomized Controlled Trials
Nutrition Reviews,
2025
DOI:10.1093/nutrit/nuae076
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[4]
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The Effects of Combined Scutellaria and Saffron Supplementation on Mood Regulation in Participants with Mild-to-Moderate Depressive Symptoms: A Randomized, Double-Blind, Placebo-Controlled Study
Nutrients,
2025
DOI:10.3390/nu17050809
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[5]
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Antidepressive synergism between crocin and D-AP5 in acute restraint-stressed mice
Behavioural Pharmacology,
2024
DOI:10.1097/FBP.0000000000000784
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[6]
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Pharmacological Mechanism of Herbal Interventions for Bipolar Disorder
Current Pharmaceutical Design,
2024
DOI:10.2174/0113816128312442240519184440
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Potential therapeutic effects of crocin
Naunyn-Schmiedeberg's Archives of Pharmacology,
2024
DOI:10.1007/s00210-024-03131-6
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[8]
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Potential therapeutic effects of crocin
Naunyn-Schmiedeberg's Archives of Pharmacology,
2024
DOI:10.1007/s00210-024-03131-6
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[9]
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Effect of Saffron Versus Selective Serotonin Reuptake Inhibitors (SSRIs) in Treatment of Depression and Anxiety: A Meta-analysis of Randomized Controlled Trials
Nutrition Reviews,
2024
DOI:10.1093/nutrit/nuae076
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The Effect of the Rice Endosperm Protein Hydrolysate on the Subjective Negative Mood Status in Healthy Humans: A Randomized, Double-Blind, and Placebo-Controlled Clinical Trial
Nutrients,
2023
DOI:10.3390/nu15153491
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[11]
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Saffron extract interferes with lipopolysaccharide-induced brain activation of the kynurenine pathway and impairment of monoamine neurotransmission in mice
Frontiers in Nutrition,
2023
DOI:10.3389/fnut.2023.1267839
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[12]
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An evaluation on potential anti-oxidant and anti-inflammatory effects of Crocin
Biomedicine & Pharmacotherapy,
2022
DOI:10.1016/j.biopha.2022.113297
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[13]
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Safety Assessment and Pain Relief Properties of Saffron from Taliouine Region (Morocco)
Molecules,
2022
DOI:10.3390/molecules27103339
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[14]
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Anti-Depressant Properties of Crocin Molecules in Saffron
Molecules,
2022
DOI:10.3390/molecules27072076
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[15]
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Saffron Extract Attenuates Anxiogenic Effect and Improves Cognitive Behavior in an Adult Zebrafish Model of Traumatic Brain Injury
International Journal of Molecular Sciences,
2022
DOI:10.3390/ijms231911600
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[16]
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Current Knowledge of the Antidepressant Activity of Chemical Compounds from Crocus sativus L.
Pharmaceuticals,
2022
DOI:10.3390/ph16010058
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[17]
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An evaluation on potential anti-oxidant and anti-inflammatory effects of Crocin
Biomedicine & Pharmacotherapy,
2022
DOI:10.1016/j.biopha.2022.113297
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[18]
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Translational Informatics for Natural Products as Antidepressant Agents
Frontiers in Cell and Developmental Biology,
2022
DOI:10.3389/fcell.2021.738838
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[19]
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The Pharmacological Activities of Crocus sativus L.: A Review Based on the Mechanisms and Therapeutic Opportunities of its Phytoconstituents
Oxidative Medicine and Cellular Longevity,
2022
DOI:10.1155/2022/8214821
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[20]
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Therapeutic effects of saffron extract on different memory types, anxiety, and hippocampal BDNF and TNF-α gene expressions in sub-chronically stressed rats
Nutritional Neuroscience,
2022
DOI:10.1080/1028415X.2021.1943138
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[21]
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Anti-Depressant Properties of Crocin Molecules in Saffron
Molecules,
2022
DOI:10.3390/molecules27072076
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[22]
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Safety Assessment and Pain Relief Properties of Saffron from Taliouine Region (Morocco)
Molecules,
2022
DOI:10.3390/molecules27103339
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[23]
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Therapeutic application and toxicity associated with Crocus sativus (saffron) and its phytochemicals
Pharmacological Research - Modern Chinese Medicine,
2022
DOI:10.1016/j.prmcm.2022.100136
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[24]
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An evaluation on potential anti-oxidant and anti-inflammatory effects of Crocin
Biomedicine & Pharmacotherapy,
2022
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[25]
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Saffron Extract Attenuates Anxiogenic Effect and Improves Cognitive Behavior in an Adult Zebrafish Model of Traumatic Brain Injury
International Journal of Molecular Sciences,
2022
DOI:10.3390/ijms231911600
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[26]
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Natural product-based pharmacological studies for neurological disorders
Frontiers in Pharmacology,
2022
DOI:10.3389/fphar.2022.1011740
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[27]
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Current Knowledge of the Antidepressant Activity of Chemical Compounds from Crocus sativus L.
Pharmaceuticals,
2022
DOI:10.3390/ph16010058
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[28]
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Affron® and increase in positive mood: evaluation of a health claim pursuant to Article 13(5) of Regulation (EC) No 1924/2006
EFSA Journal,
2021
DOI:10.2903/j.efsa.2021.6669
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[29]
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The Impact of Crocin and Chronic Isolation Stress on Passive Avoidance Memory and Brain Electrical Activity in Male Rats
Physiology and Pharmacology,
2021
DOI:10.52547/phypha.26.4.3
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[30]
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Saffron Extract-Induced Improvement of Depressive-Like Behavior in Mice Is Associated with Modulation of Monoaminergic Neurotransmission
Nutrients,
2021
DOI:10.3390/nu13030904
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[31]
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The Effect of Eight Weeks of Endurance Training with Saffron on miR133bFC, miR29aFC in the Hippocampus Tissue and Depression in Rats with Alzheimer’s Disease
Jundishapur Journal of Natural Pharmaceutical Products,
2021
DOI:10.5812/jjnpp.103333
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[32]
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Comparing the effects of crocin at different doses on excitability and long-term potentiation in the CA1 area, as well as the electroencephalogram responses of rats under chronic stress
Metabolic Brain Disease,
2021
DOI:10.1007/s11011-021-00747-y
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[33]
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Saffron extract attenuates neuroinflammation in rmTBI mouse model by suppressing NLRP3 inflammasome activation via SIRT1
PLOS ONE,
2021
DOI:10.1371/journal.pone.0257211
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[34]
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Prevention of Stress-Induced Depressive-like Behavior by Saffron Extract Is Associated with Modulation of Kynurenine Pathway and Monoamine Neurotransmission
Pharmaceutics,
2021
DOI:10.3390/pharmaceutics13122155
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[35]
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Saffron Extract-Induced Improvement of Depressive-Like Behavior in Mice Is Associated with Modulation of Monoaminergic Neurotransmission
Nutrients,
2021
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[36]
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Prevention of Stress-Induced Depressive-like Behavior by Saffron Extract Is Associated with Modulation of Kynurenine Pathway and Monoamine Neurotransmission
Pharmaceutics,
2021
DOI:10.3390/pharmaceutics13122155
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[37]
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Affron® and increase in positive mood: evaluation of a health claim pursuant to Article 13(5) of Regulation (EC) No 1924/2006
EFSA Journal,
2021
DOI:10.2903/j.efsa.2021.6669
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[38]
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The effect of crocin (the main active saffron constituent) on the cognitive functions, craving, and withdrawal syndrome in opioid patients under methadone maintenance treatment
Phytotherapy Research,
2021
DOI:10.1002/ptr.6913
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[39]
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Herbal medicines and phytochemicals for obsessive–compulsive disorder
Phytotherapy Research,
2020
DOI:10.1002/ptr.6656
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[40]
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Therapeutic potentials of crocin in medication of neurological disorders
Food and Chemical Toxicology,
2020
DOI:10.1016/j.fct.2020.111739
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[41]
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Saffron
2020
DOI:10.1016/B978-0-12-818462-2.00008-5
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[42]
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2020
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Saffron
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Herbal medicines and phytochemicals for obsessive–compulsive disorder
Phytotherapy Research,
2020
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[45]
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The effect of crocin (the main active saffron constituent) on the cognitive functions, craving, and withdrawal syndrome in opioid patients under methadone maintenance treatment
Phytotherapy Research,
2020
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[46]
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Role of Muscarinic Receptors in Hypoalgesia Induced by Crocin in Neuropathic Pain Rats
The Scientific World Journal,
2020
DOI:10.1155/2020/4046256
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[47]
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Saffron (Crocus sativus) aqueous extract reverses the hypothalamus-pituitary-adrenal axis activity in rat model of post-traumatic stress disorder
Revista Brasileira de Farmacognosia,
2019
DOI:10.1016/j.bjp.2019.01.011
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Effect of saffron supplementation on symptoms of depression and anxiety: a systematic review and meta-analysis
Nutrition Reviews,
2019
DOI:10.1093/nutrit/nuz023
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Sleep Promoting Effects of IQP-AO-101: A Double-Blind, Randomized, Placebo-Controlled Exploratory Trial
Evidence-Based Complementary and Alternative Medicine,
2019
DOI:10.1155/2019/9178218
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[50]
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Efficacy of a standardised saffron extract (affron®) as an add-on to antidepressant medication for the treatment of persistent depressive symptoms in adults: A randomised, double-blind, placebo-controlled study
Journal of Psychopharmacology,
2019
DOI:10.1177/0269881119867703
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Efficacy of a standardised saffron extract (affron®) as an add-on to antidepressant medication for the treatment of persistent depressive symptoms in adults: A randomised, double-blind, placebo-controlled study
Journal of Psychopharmacology,
2019
DOI:10.1177/0269881119867703
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Phytochemistry and pharmacology of anti-depressant medicinal plants: A review
Biomedicine & Pharmacotherapy,
2018
DOI:10.1016/j.biopha.2018.05.044
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Phytochemistry and pharmacology of anti-depressant medicinal plants: A review
Biomedicine & Pharmacotherapy,
2018
DOI:10.1016/j.biopha.2018.05.044
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affron ® , a standardised extract from saffron (Crocus sativus L.) for the treatment of youth anxiety and depressive symptoms: A randomised, double-blind, placebo-controlled study
Journal of Affective Disorders,
2018
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Physiological/Neurophysiological Mechanisms Involved in the Formation of Stress Responses
Neurophysiology,
2018
DOI:10.1007/s11062-018-9727-1
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[56]
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The Prophylactic and Therapeutic Effects of Saffron Extract and Crocin on Ethanol Withdrawal Syndrome in Mice
Journal of Pharmacopuncture,
2018
DOI:10.3831/KPI.2018.21.031
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[57]
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Phytochemistry and pharmacology of anti-depressant medicinal plants: A review
Biomedicine & Pharmacotherapy,
2018
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[58]
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Phytochemistry and pharmacology of anti-depressant medicinal plants: A review
Biomedicine & Pharmacotherapy,
2018
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[59]
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affron ® a novel saffron extract ( Crocus sativus L .) improves mood in healthy adults over 4 weeks in a double-blind, parallel, randomized, placebo-controlled clinical trial
Complementary Therapies in Medicine,
2017
DOI:10.1016/j.ctim.2017.06.001
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[60]
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Effects of Crocin on Learning and Memory in Rats Under Chronic Restraint Stress with Special Focus on the Hippocampal and Frontal Cortex Corticosterone Levels
Advanced Biomedical Research,
2017
DOI:10.4103/abr.abr_107_17
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[61]
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The Psychoactive Agent Crocin Can Regulate Hypothalamic-Pituitary-Adrenal Axis Activity
Frontiers in Neuroscience,
2017
DOI:10.3389/fnins.2017.00668
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[62]
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Effect of Saffron (Crocus Satious L.) as an Add-On Therapy to Sertraline in Mild to Moderate Generalized Anxiety Disorder: A Double Blind Randomized Controlled Trial
Archives of Neuroscience,
2017
DOI:10.5812/archneurosci.14332
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[63]
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Evidence of neuroprotective effects of saffron and crocin in a Drosophila model of parkinsonism
NeuroToxicology,
2016
DOI:10.1016/j.neuro.2015.12.010
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