Author(s)

Ruchee Phonchai^1,2, Pimjai Naigowit², Bunchob Ubonsaen³, Supansa Nilubol², Supaluk Brameld⁴, Parinya Noisa^1*

¹Laboratory of Cell-Based Assay and Innovations, Biotechnology, Suranaree University of Technology, Nakhon Ratchasima, Thailand.
²LBM Stem Cell Research Unit, Life Balance Methodology Co., Ltd., Bangkok, Thailand.
³Sangkhom Hospital, Nongkhai Provincial Health Office, Nongkhai, Thailand.
⁴National Institute of Health, Ministry of Public Health, Nonthaburi, Thailand.

Atrophic scars, a permanent complication of severe acne, have negative effect on psychology in adolescent. The treatment of atrophic scar is depended on types of scar and it is difficult to improve by a single treatment. Mesenchymal stem cell is a scientific approval for surgery scar treatment and wound healing. We present a case report of female presented with atrophic acne scar distributed on both cheeks. The case aims to prove that the combination of MSCs and aqueous human placenta extract (RGF®) contained bioactive therapeutic molecules obviously promoted the improvement of skin scar to reach the optimal outcomes. We first found that MSCs-contained human placenta extract solution combination subcision improves the atrophic acne scar and skin complexity by enhancement of skin cell regeneration.

Atrophic Scar, Mesenchymal Stem Cells, Human Placenta Extract, Mesotherapy, Skin, Regeneration

Phonchai, R. , Naigowit, P. , Ubonsaen, B. , Nilubol, S. , Brameld, S. and Noisa, P. (2020) Improvement of Atrophic Acne Scar and Skin Complexity by Combination of Aqueous Human Placenta Extract and Mesenchymal Stem Cell Mesotherapy. Journal of Cosmetics, Dermatological Sciences and Applications, 10, 1-7. doi: 10.4236/jcdsa.2020.101001.