Author(s)

Raghad Alajlani, Amal Alssadi

Faculty of Science, Chemistry Department, King Abdulaziz University, Jeddah, Saudi Arabia.

Many of the technology and computational chemistry applications are used to study drugs and their biological effects. Flutab® drug contains Paracetamol, Diphenhydramine and Pseudoephedrine. Ab-initio calculations were performed at DFT/B3LYP and HF methods with three basis sets, namely, STO-3G, 3-21G, and 6-31G(d) in order to calculate the dipole moments of the three constituents of Flutab® drug. The Diphenhydramine compound was found to be the most stable constituent, with the lowest value of dipole moment.

Flutab®, DFT Calculations, HF Calculations, Dipole Moment

Alajlani, R. and Alssadi, A. (2019) Dipole Moments of the Bioactive Constituents Present in Flutab Drug by Ab-Initio Calculations. Open Journal of Physical Chemistry, 9, 216-220. doi: 10.4236/ojpc.2019.94013.