Error Analysis for Protein Conformation Quantities in Circular Dichroism Spectrum - Open Access Library Journal

OALibJ > Vol.5 No.11, November 2018

Error Analysis for Protein Conformation Quantities in Circular Dichroism Spectrum ()

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DOI: 10.4236/oalib.1104966 542 Downloads 1,146 Views Citations

Author(s)

David A. Haner, Patrick W. Mobley

Affiliation(s)

Department of Chemistry and Biochemistry, California State Polytechnic University, Pomona, California, USA.

ABSTRACT

The object of this paper is to present the development of the uncertainties of the parameter values produced by an algorithm for a mathematical model based on the spectroscopic signature of iconic conformations. Emphasis is given to including the systematic experimental error simultaneously with primary measured data and the use of fully determined solution of equations to unknowns. To demonstrate the details of finding the parameter uncertainties, the data from two independent publications are joined.

KEYWORDS

Circular Dichroism, Protein Secondary Structure, Singular Value Decomposition, Error

Share and Cite:

Haner, D. and Mobley, P. (2018) Error Analysis for Protein Conformation Quantities in Circular Dichroism Spectrum. Open Access Library Journal, 5, 1-11. doi: 10.4236/oalib.1104966.

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